Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake
Oral bisphosphonates are approved for the treatment of bone loss associated with several conditions including postmenopausal osteoporosis. Although generally well tolerated, adverse effects such as gastroesophageal reflux and oesophageal and peptic ulceration may occur. Oral mucositis and ulceration...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/6620489 |
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| _version_ | 1850214445484081152 |
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| author | Manju Chandran Wanling Zeng |
| author_facet | Manju Chandran Wanling Zeng |
| author_sort | Manju Chandran |
| collection | DOAJ |
| description | Oral bisphosphonates are approved for the treatment of bone loss associated with several conditions including postmenopausal osteoporosis. Although generally well tolerated, adverse effects such as gastroesophageal reflux and oesophageal and peptic ulceration may occur. Oral mucositis and ulceration are lesser-known side effects. Proper counselling and rigorous adherence to the administration instructions are crucial. We describe a case of bisphosphonate-induced severe oral mucosal ulceration in an elderly woman that was caused by incorrect instructions and/or incorrect understanding of instructions for oral alendronate intake. |
| format | Article |
| id | doaj-art-85677ca6fd4c45f99eb6cab0cb71eeeb |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-85677ca6fd4c45f99eb6cab0cb71eeeb2025-08-20T02:08:54ZengWileyCase Reports in Medicine1687-96271687-96352021-01-01202110.1155/2021/66204896620489Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and IntakeManju Chandran0Wanling Zeng1Complicated Metabolic Bone Disorders Clinic, Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Bukit Merah, SingaporeDepartment of Endocrinology, Singapore General Hospital, Bukit Merah, SingaporeOral bisphosphonates are approved for the treatment of bone loss associated with several conditions including postmenopausal osteoporosis. Although generally well tolerated, adverse effects such as gastroesophageal reflux and oesophageal and peptic ulceration may occur. Oral mucositis and ulceration are lesser-known side effects. Proper counselling and rigorous adherence to the administration instructions are crucial. We describe a case of bisphosphonate-induced severe oral mucosal ulceration in an elderly woman that was caused by incorrect instructions and/or incorrect understanding of instructions for oral alendronate intake.http://dx.doi.org/10.1155/2021/6620489 |
| spellingShingle | Manju Chandran Wanling Zeng Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake Case Reports in Medicine |
| title | Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake |
| title_full | Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake |
| title_fullStr | Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake |
| title_full_unstemmed | Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake |
| title_short | Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake |
| title_sort | severe oral mucosal ulceration associated with oral bisphosphonate use the importance of imparting proper instructions on medication administration and intake |
| url | http://dx.doi.org/10.1155/2021/6620489 |
| work_keys_str_mv | AT manjuchandran severeoralmucosalulcerationassociatedwithoralbisphosphonateusetheimportanceofimpartingproperinstructionsonmedicationadministrationandintake AT wanlingzeng severeoralmucosalulcerationassociatedwithoralbisphosphonateusetheimportanceofimpartingproperinstructionsonmedicationadministrationandintake |