The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas

A 62-year-old woman undergoing embolization of recurrent neuroendocrine tumor, positive for serotonin, developed chest pain and bradycardia with lateral ST-segment depression. Cardiac biomarkers were elevated, and echocardiography revealed akinesis of all basal segments with a normally contracting a...

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Main Authors: Ian A. Mazzetti, Michael J. Marcaccio, Odette Boutross-Tadross, Omid Salehian, Catherine Demers
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/793193
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author Ian A. Mazzetti
Michael J. Marcaccio
Odette Boutross-Tadross
Omid Salehian
Catherine Demers
author_facet Ian A. Mazzetti
Michael J. Marcaccio
Odette Boutross-Tadross
Omid Salehian
Catherine Demers
author_sort Ian A. Mazzetti
collection DOAJ
description A 62-year-old woman undergoing embolization of recurrent neuroendocrine tumor, positive for serotonin, developed chest pain and bradycardia with lateral ST-segment depression. Cardiac biomarkers were elevated, and echocardiography revealed akinesis of all basal segments with a normally contracting apex. The absence of flow-limiting coronary disease on angiography confirmed the presence of reverse Takotsubo cardiomyopathy. After optimal medical therapy for six weeks, left ventricular function returned to normal. Takotsubo cardiomyopathy has been described across a wide variety of hyperadrenergic states; the description of the reverse-type Takotsubo cardiomyopathy in the setting of embolization of recurrent neuroendocrine with serotonergic positivity tumour is novel.
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series Case Reports in Medicine
spelling doaj-art-855cf6a2539d44779d06428da886326d2025-02-03T06:07:03ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/793193793193The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the PancreasIan A. Mazzetti0Michael J. Marcaccio1Odette Boutross-Tadross2Omid Salehian3Catherine Demers4McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, CanadaDepartment of Surgery, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, CanadaDepartment of Pathology and Molecular Medicine, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, CanadaDivision of Cardiology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, CanadaDivision of Cardiology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, CanadaA 62-year-old woman undergoing embolization of recurrent neuroendocrine tumor, positive for serotonin, developed chest pain and bradycardia with lateral ST-segment depression. Cardiac biomarkers were elevated, and echocardiography revealed akinesis of all basal segments with a normally contracting apex. The absence of flow-limiting coronary disease on angiography confirmed the presence of reverse Takotsubo cardiomyopathy. After optimal medical therapy for six weeks, left ventricular function returned to normal. Takotsubo cardiomyopathy has been described across a wide variety of hyperadrenergic states; the description of the reverse-type Takotsubo cardiomyopathy in the setting of embolization of recurrent neuroendocrine with serotonergic positivity tumour is novel.http://dx.doi.org/10.1155/2013/793193
spellingShingle Ian A. Mazzetti
Michael J. Marcaccio
Odette Boutross-Tadross
Omid Salehian
Catherine Demers
The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
Case Reports in Medicine
title The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
title_full The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
title_fullStr The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
title_full_unstemmed The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
title_short The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Serotonin-Positive Neuroendocrine Tumour of the Pancreas
title_sort ace of spades reverse takotsubo cardiomyopathy in the context of angiographic embolization of recurrent metastatic serotonin positive neuroendocrine tumour of the pancreas
url http://dx.doi.org/10.1155/2013/793193
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