First-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis

First-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis

Predicting long-term prognosis and choosing the appropriate therapeutic approach in patients with Multiple Sclerosis (MS) at the time of diagnosis is crucial in view of a personalized medicine. We investigated the impact of early therapeutic response on the 5-year prognosis of patients with relapsin...

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Main Authors: Simona Toscano, Tim Spelman, Serkan Ozakbas, Raed Alroughani, Clara G. Chisari, Salvatore Lo Fermo, Alexandre Prat, Marc Girard, Pierre Duquette, Guillermo Izquierdo, Sara Eichau, Pierre Grammond, Cavit Boz, Tomas Kalincik, Yolanda Blanco, Katherine Buzzard, Olga Skibina, Maria Jose Sa, Anneke van der Walt, Helmut Butzkueven, Murat Terzi, Oliver Gerlach, Francois Grand'Maison, Matteo Foschi, Andrea Surcinelli, Michael Barnett, Alessandra Lugaresi, Marco Onofrj, Bassem Yamout, Samia J. Khoury, Julie Prevost, Jeannette Lechner-Scott, Davide Maimone, Maria Pia Amato, Daniele Spitaleri, Vincent Van Pesch, Richard Macdonell, Elisabetta Cartechini, Koen de Gans, Mark Slee, Tamara Castillo-Triviño, Aysun Soysal, Jose Luis Sanchez-Menoyo, Guy Laureys, Liesbeth Van Hijfte, Pamela McCombe, Ayse Altintas, Bianca Weinstock-Guttman, Eduardo Aguera-Morales, Masoud Etemadifar, Cristina Ramo-Tello, Nevin John, Recai Turkoglu, Suzanne Hodgkinson, Sarah Besora, Bart Van Wijmeersch, Ricardo Fernandez-Bolaños, Francesco Patti
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neurotherapeutics
Subjects:
Multiple sclerosis
Disease-modifying treatment
Prognosis
Nomogram
High-efficacy drugs
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747925000303
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