Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography
The purpose of this study is to identify the prevalence of osteoporosis in male patients with chronic obstructive pulmonary disease (COPD) by dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) and to compare the diagnostic abilities of the above methods. Thirty-seven m...
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Wiley
2016-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/6169721 |
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| author | George Fountoulis Theodora Kerenidi Constantinos Kokkinis Panagiotis Georgoulias Paschal Thriskos Konstantinos Gourgoulianis Ioannis Fezoulidis Katerina Vassiou Marianna Vlychou |
| author_facet | George Fountoulis Theodora Kerenidi Constantinos Kokkinis Panagiotis Georgoulias Paschal Thriskos Konstantinos Gourgoulianis Ioannis Fezoulidis Katerina Vassiou Marianna Vlychou |
| author_sort | George Fountoulis |
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| description | The purpose of this study is to identify the prevalence of osteoporosis in male patients with chronic obstructive pulmonary disease (COPD) by dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) and to compare the diagnostic abilities of the above methods. Thirty-seven male patients with established COPD were examined with DXA and standard QCT in lumbar spine, including L1, L2, and L3 vertebrae. T-scores and bone mineral density values were calculated by DXA and QCT method, respectively. Comparative assessment of the findings was performed and statistical analysis was applied. QCT measurements found more COPD patients with impaired bone mineral density compared to DXA, namely, 13 (35.1%) versus 12 (32.4%) patients with osteopenia and 16 (43.2%) versus 9 (16.2%) patients with osteoporosis (p=0.04). More vertebrae were found with osteoporosis by QCT compared to DXA (p=0.03). The prevalence of osteoporosis among male patients with COPD is increased and DXA may underestimate this risk. QCT measurements have an improved discriminating ability to identify low BMD compared to DXA measurements because QCT is able to overcome diagnostic pitfalls including aortic calcifications and degenerative spinal osteophytes. |
| format | Article |
| id | doaj-art-855a3df5be654d37835babbe2aada01b |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-855a3df5be654d37835babbe2aada01b2025-02-03T05:48:14ZengWileyInternational Journal of Endocrinology1687-83371687-83452016-01-01201610.1155/2016/61697216169721Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed TomographyGeorge Fountoulis0Theodora Kerenidi1Constantinos Kokkinis2Panagiotis Georgoulias3Paschal Thriskos4Konstantinos Gourgoulianis5Ioannis Fezoulidis6Katerina Vassiou7Marianna Vlychou8Department of Radiology, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreecePulmonology Clinic, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceDepartment of Radiology, KAT Hospital, 14561 Athens, GreeceDepartment of Nuclear Medicine, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceDepartment of Radiology, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreecePulmonology Clinic, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceDepartment of Radiology, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceDepartment of Radiology, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceDepartment of Radiology, University Hospital of Larissa, University of Thessaly, School of Medicine, Biopolis, 41110 Larissa, GreeceThe purpose of this study is to identify the prevalence of osteoporosis in male patients with chronic obstructive pulmonary disease (COPD) by dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) and to compare the diagnostic abilities of the above methods. Thirty-seven male patients with established COPD were examined with DXA and standard QCT in lumbar spine, including L1, L2, and L3 vertebrae. T-scores and bone mineral density values were calculated by DXA and QCT method, respectively. Comparative assessment of the findings was performed and statistical analysis was applied. QCT measurements found more COPD patients with impaired bone mineral density compared to DXA, namely, 13 (35.1%) versus 12 (32.4%) patients with osteopenia and 16 (43.2%) versus 9 (16.2%) patients with osteoporosis (p=0.04). More vertebrae were found with osteoporosis by QCT compared to DXA (p=0.03). The prevalence of osteoporosis among male patients with COPD is increased and DXA may underestimate this risk. QCT measurements have an improved discriminating ability to identify low BMD compared to DXA measurements because QCT is able to overcome diagnostic pitfalls including aortic calcifications and degenerative spinal osteophytes.http://dx.doi.org/10.1155/2016/6169721 |
| spellingShingle | George Fountoulis Theodora Kerenidi Constantinos Kokkinis Panagiotis Georgoulias Paschal Thriskos Konstantinos Gourgoulianis Ioannis Fezoulidis Katerina Vassiou Marianna Vlychou Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography International Journal of Endocrinology |
| title | Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography |
| title_full | Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography |
| title_fullStr | Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography |
| title_full_unstemmed | Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography |
| title_short | Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography |
| title_sort | assessment of bone mineral density in male patients with chronic obstructive pulmonary disease by dxa and quantitative computed tomography |
| url | http://dx.doi.org/10.1155/2016/6169721 |
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