Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots
This paper describes the seasonal phytochemical variation and the antimicrobial potential of V. zizanioides roots collected in Brazil. Considering the high levels of chemical constituents and their biological activity in dichloromethane fraction, the plants were grown in different seasons and the re...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2014-12-01
|
| Series: | Acta Pharmaceutica |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acph-2014-0040 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832569200550346752 |
|---|---|
| author | Dos Santos Delair Silveira Oberger Júlia Vieira Niero Rivaldo Wagner Theodoro Delle Monache Franco Cruz Alexandre Bella Martin-Quintal Zhelmy Cechinel Filho Valdir |
| author_facet | Dos Santos Delair Silveira Oberger Júlia Vieira Niero Rivaldo Wagner Theodoro Delle Monache Franco Cruz Alexandre Bella Martin-Quintal Zhelmy Cechinel Filho Valdir |
| author_sort | Dos Santos Delair Silveira |
| collection | DOAJ |
| description | This paper describes the seasonal phytochemical variation and the antimicrobial potential of V. zizanioides roots collected in Brazil. Considering the high levels of chemical constituents and their biological activity in dichloromethane fraction, the plants were grown in different seasons and the respective dichloromethane fractions were analyzed by gas chromatography-mass spectrometry. The antimicrobial activity was evaluated against several pathogenic microorganisms by determining the minimum inhibitory concentration (MIC) using the agar dilution method. Yields of dichloromethane fractions from plants collected in the autumn and spring occurred in a higher proportion than in other seasons. Khusimol (2) was isolated by column chromatography and identified by NMR and CG-MS, along with other sesquiterpenes, including β-vetivenene (1), vetiselinenol (3), isovalencenol (4), vetivenic acid (5), α-vetivone (6) and β-vetivone (7). Some extracts showed promising antimicrobial effects, with MICs ranging from 31.25 to 500 μg mL-1. Kushimol was slightly active against the tested microorganisms. |
| format | Article |
| id | doaj-art-853f4884783d469899a8c6242d8c17cd |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-853f4884783d469899a8c6242d8c17cd2025-02-02T23:02:22ZengSciendoActa Pharmaceutica1846-95582014-12-0164449550110.2478/acph-2014-0040acph-2014-0040Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides rootsDos Santos Delair Silveira0Oberger Júlia Vieira1Niero Rivaldo2Wagner Theodoro3Delle Monache Franco4Cruz Alexandre Bella5Martin-Quintal Zhelmy6Cechinel Filho Valdir7Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilUniversidad Autónoma de Yucatán (UADY) Calle 41 No 421 x 26 y 28 Col. Industrial, C.P. 97150, Mérida Yucatán, MexicoPrograma de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, BrazilThis paper describes the seasonal phytochemical variation and the antimicrobial potential of V. zizanioides roots collected in Brazil. Considering the high levels of chemical constituents and their biological activity in dichloromethane fraction, the plants were grown in different seasons and the respective dichloromethane fractions were analyzed by gas chromatography-mass spectrometry. The antimicrobial activity was evaluated against several pathogenic microorganisms by determining the minimum inhibitory concentration (MIC) using the agar dilution method. Yields of dichloromethane fractions from plants collected in the autumn and spring occurred in a higher proportion than in other seasons. Khusimol (2) was isolated by column chromatography and identified by NMR and CG-MS, along with other sesquiterpenes, including β-vetivenene (1), vetiselinenol (3), isovalencenol (4), vetivenic acid (5), α-vetivone (6) and β-vetivone (7). Some extracts showed promising antimicrobial effects, with MICs ranging from 31.25 to 500 μg mL-1. Kushimol was slightly active against the tested microorganisms.https://doi.org/10.2478/acph-2014-0040vetiveria zizanioides (poaceae)seasonalitysesquiterpeneskhusimolantimicrobial activity |
| spellingShingle | Dos Santos Delair Silveira Oberger Júlia Vieira Niero Rivaldo Wagner Theodoro Delle Monache Franco Cruz Alexandre Bella Martin-Quintal Zhelmy Cechinel Filho Valdir Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots Acta Pharmaceutica vetiveria zizanioides (poaceae) seasonality sesquiterpenes khusimol antimicrobial activity |
| title | Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots |
| title_full | Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots |
| title_fullStr | Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots |
| title_full_unstemmed | Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots |
| title_short | Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots |
| title_sort | seasonal phytochemical study and antimicrobial potential of vetiveria zizanioides roots |
| topic | vetiveria zizanioides (poaceae) seasonality sesquiterpenes khusimol antimicrobial activity |
| url | https://doi.org/10.2478/acph-2014-0040 |
| work_keys_str_mv | AT dossantosdelairsilveira seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT obergerjuliavieira seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT nierorivaldo seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT wagnertheodoro seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT dellemonachefranco seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT cruzalexandrebella seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT martinquintalzhelmy seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots AT cechinelfilhovaldir seasonalphytochemicalstudyandantimicrobialpotentialofvetiveriazizanioidesroots |