From gut inflammation to psychiatric comorbidity: mechanisms and therapies for anxiety and depression in inflammatory bowel disease

From gut inflammation to psychiatric comorbidity: mechanisms and therapies for anxiety and depression in inflammatory bowel disease

Abstract Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is characterized by complex aetiological factors and extensive extraintestinal manifestations. Anxiety and depression, which are common mental disorders, have shown increasing incidence rates...

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Bibliographic Details
Main Authors: Kangcheng Luo, Mengting Zhang, Qianwen Tu, Jian Li, Youheng Wang, Songlin Wan, Daojiang Li, Qun Qian, Lu Xia
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Neuroinflammation
Subjects:
Depression
Anxiety
Inflammatory bowel disease
Microbiota‒gut‒brain axis
Neuroimmune
Pharmacotherapy
Online Access:https://doi.org/10.1186/s12974-025-03476-6
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