Lung Cavity and Endobronchial Mass: An Uncommon Initial Presentation of Hodgkin's Lymphoma

ABSTRACT Constitutional symptoms and lymphadenopathy are cardinal features of Hodgkin's lymphoma (HL), a malignant lymphoproliferative disorder. While mediastinal involvement is frequently observed, endobronchial HL is a rare and challenging presentation. We report a 23‐year‐old gentleman who p...

Full description

Saved in:
Bibliographic Details
Main Authors: Peter Natarajan, Khai Lip Ng, Nai‐Chien Huan, Ad Rian Chong, Najah Momin, Nur Husna Mohd Aminudin, Nor Hafizah Abu Hassan, Kasuma Mohamed Nordin
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.70254
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT Constitutional symptoms and lymphadenopathy are cardinal features of Hodgkin's lymphoma (HL), a malignant lymphoproliferative disorder. While mediastinal involvement is frequently observed, endobronchial HL is a rare and challenging presentation. We report a 23‐year‐old gentleman who presented with a persistent cough, weight loss and a large cavitating lung mass. Microbiological investigations yielded negative results but flexible bronchoscopy (FB) revealed multiple endobronchial masses. Subsequent pathological examination confirmed the diagnosis of HL, mixed cellularity subtype. This case highlights the importance of considering HL in the differentials of endobronchial masses and lung cavities, particularly when initial investigations fail to identify a clear cause.
ISSN:2051-3380