Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report

Intraductal papillary neoplasms of the bile ducts (IPNBs) represent a rare biliary tract tumors with malignant potential, requiring surgical resection to prevent progression to cholangiocarcinoma. In this case, an 83-year-old woman with an obstructive pattern in liver function tests was incidentally...

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Main Authors: Imene Chafai, MD, Alba Igual-Rouilleault, MD PhD, Morgane Van Wettere, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325005564
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author Imene Chafai, MD
Alba Igual-Rouilleault, MD PhD
Morgane Van Wettere, MD
author_facet Imene Chafai, MD
Alba Igual-Rouilleault, MD PhD
Morgane Van Wettere, MD
author_sort Imene Chafai, MD
collection DOAJ
description Intraductal papillary neoplasms of the bile ducts (IPNBs) represent a rare biliary tract tumors with malignant potential, requiring surgical resection to prevent progression to cholangiocarcinoma. In this case, an 83-year-old woman with an obstructive pattern in liver function tests was incidentally found to have a solid mass in the left hepatic lobe on ultrasound. Liver MRI suggested a polypoid intraductal papillary neoplasm of the left bile duct, and histopathological analysis after surgical resection confirmed low-grade dysplasia with a pancreaticobiliary subtype. Postoperative MRI showed no residual tumor, and the patient remains under close observation with no evidence of recurrence. This case highlights the importance of imaging techniques in the early detection and characterization of IPNB, and includes a summary of its morphological subtypes.
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spelling doaj-art-8516a1af9d1c46948ebbea8a3f85d3af2025-08-20T03:33:56ZengElsevierRadiology Case Reports1930-04332025-09-012094695470010.1016/j.radcr.2025.06.008Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case reportImene Chafai, MD0Alba Igual-Rouilleault, MD PhD1Morgane Van Wettere, MD2Department of Radiology, Erasme University Hospital, Brussels, Belgium; Corresponding author.Department of Abdominal Radiology, Cliniques Universitaires Saint-Luc, Brussels, BelgiumDepartment of Radiology, Erasme University Hospital, Brussels, BelgiumIntraductal papillary neoplasms of the bile ducts (IPNBs) represent a rare biliary tract tumors with malignant potential, requiring surgical resection to prevent progression to cholangiocarcinoma. In this case, an 83-year-old woman with an obstructive pattern in liver function tests was incidentally found to have a solid mass in the left hepatic lobe on ultrasound. Liver MRI suggested a polypoid intraductal papillary neoplasm of the left bile duct, and histopathological analysis after surgical resection confirmed low-grade dysplasia with a pancreaticobiliary subtype. Postoperative MRI showed no residual tumor, and the patient remains under close observation with no evidence of recurrence. This case highlights the importance of imaging techniques in the early detection and characterization of IPNB, and includes a summary of its morphological subtypes.http://www.sciencedirect.com/science/article/pii/S1930043325005564IPNBBile ductMRICholangiocarcinoma
spellingShingle Imene Chafai, MD
Alba Igual-Rouilleault, MD PhD
Morgane Van Wettere, MD
Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
Radiology Case Reports
IPNB
Bile duct
MRI
Cholangiocarcinoma
title Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
title_full Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
title_fullStr Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
title_full_unstemmed Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
title_short Incidental diagnosis of intraductal papillary neoplasm of the bile duct: Imaging findings from a case report
title_sort incidental diagnosis of intraductal papillary neoplasm of the bile duct imaging findings from a case report
topic IPNB
Bile duct
MRI
Cholangiocarcinoma
url http://www.sciencedirect.com/science/article/pii/S1930043325005564
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