The correlation between insulin resistance and blood lipids in children
Background: This work focused on the correlation between insulin resistance (IR) and blood lipids (BL) in children with simple obesity, as well as the intervention effects of high-intensity interval training (HIIT) in weight loss in children. Methods: 80 children aged 6 to 17 years with simple obesi...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Society of Medical Biochemists of Serbia, Belgrade
2024-01-01
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| Series: | Journal of Medical Biochemistry |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2024/1452-82582406860J.pdf |
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| Summary: | Background: This work focused on the correlation between insulin resistance (IR) and blood lipids (BL) in children with simple obesity, as well as the intervention effects of high-intensity interval training (HIIT) in weight loss in children. Methods: 80 children aged 6 to 17 years with simple obesity were selected from our hospital and randomly grouped into two groups. Children in the control (Ctrl) group underwent traditional moderate-intensity continuous training (MICT), while those in the other group received HIIT (HIIT group). After four weeks, body composition-related indicators, BL levels, and IR were measured. Results: After exercise, children in both groups possessed obvious reductions in body mass index (BMI), body fat percentage (BFP), triglyceride (TG), and homeostasis model assessment of IR (HOMA-IR), demonstrating remarkable differences in contrast to those after intervention (P<0.05). The HIIT group also exhibited considerable differences in waist circumference (WC), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) (P<0.05). After exercise, the HIIT group demonstrated more observable BMI, WC, TG, and HOMA-IR reductions, showing great differences with the Ctrl group (P<0.05). HOMA-IR exhibited positive correlations with TC, TG, and HDL-C but a negative one with LDL-C (P<0.05). Conclusions: HIIT improved the body composition and BL levels in children with simple obesity, downregulated HOMA-IR, and positively impacted their health status. Furthermore, IR was associated with BL-relevant indicators in children with simple obesity. |
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| ISSN: | 1452-8258 1452-8266 |