Exploring a patient-specific in vitro pipeline for stratification and drug response prediction of microglia-based therapeutics
Abstract The scarcity of effective biomarkers and therapeutic strategies for predicting disease onset and progression in neurodegenerative diseases such as Alzheimer’s disease (AD) is a major challenge. Conventional drug discovery approaches have been unsuccessful in providing efficient intervention...
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| Main Authors: | Carla Cuní-López, Romal Stewart, Satomi Okano, Garry L. Redlich, Mark W. Appleby, Anthony R. White, Hazel Quek |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-92593-6 |
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