Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs

In order to ensure a high-quality and safe therapeutic process in radionuclide therapy, it is not sufficient to rely solely on safety monitoring within the framework of production control. Measures must be implemented within a quality assurance system as established in the quality assurance program....

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Main Authors: A. V. Likhacheva, A. V. Vodovatov, L. A. Chipiga
Format: Article
Language:English
Published: Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev 2025-07-01
Series:Радиационная гигиена
Subjects:
Online Access:https://www.radhyg.ru/jour/article/view/1158
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author A. V. Likhacheva
A. V. Vodovatov
L. A. Chipiga
author_facet A. V. Likhacheva
A. V. Vodovatov
L. A. Chipiga
author_sort A. V. Likhacheva
collection DOAJ
description In order to ensure a high-quality and safe therapeutic process in radionuclide therapy, it is not sufficient to rely solely on safety monitoring within the framework of production control. Measures must be implemented within a quality assurance system as established in the quality assurance program. The purpose of this work is to define the requirements for quality assurance program in radionuclide therapy in terms of the ensuring radiation safety for patients, staff, the public, and the environment. The work discusses approaches to developing a quality assurance program in radionuclide therapy as a tool for optimizing radiation protection for patients, medical staff, and the public. The proposed structure of the quality assurance program covers all stages of radionuclide therapy – from patient identification and radiopharmaceutical quality control to the evaluation of therapeutic efficacy and safety at all levels. Particular attention is given to the need for equipment monitoring, imaging parameter control, management of biological waste, patient instruction upon discharge, as well as dosimetry-guided radionuclide therapy planning aimed at optimizing patient radiation protection. The quality assurance program in radionuclide therapy is proposed as a foundation for building a standardized, safe, and effective quality assurance system aligned with international practices, with a primary focus on personalized approaches to the planning and delivery of radionuclide therapy.
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publishDate 2025-07-01
publisher Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev
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series Радиационная гигиена
spelling doaj-art-84fc721bf07343a3a166e01a9e8d795c2025-08-20T04:00:40ZengSaint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. RamzaevРадиационная гигиена1998-426X2025-07-0118212213010.21514/1998-426X-2025-18-2-122-130914Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programsA. V. Likhacheva0A. V. Vodovatov1L. A. Chipiga2Saint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing ; The City Hospital No 40 of the Kurortny DistrictSaint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing ; Saint-Petersburg State Pediatric Medical UniversitySaint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing ; A. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian Federation ; Almazov National Medical Research Centre of the Ministry of Health of the Russian FederationIn order to ensure a high-quality and safe therapeutic process in radionuclide therapy, it is not sufficient to rely solely on safety monitoring within the framework of production control. Measures must be implemented within a quality assurance system as established in the quality assurance program. The purpose of this work is to define the requirements for quality assurance program in radionuclide therapy in terms of the ensuring radiation safety for patients, staff, the public, and the environment. The work discusses approaches to developing a quality assurance program in radionuclide therapy as a tool for optimizing radiation protection for patients, medical staff, and the public. The proposed structure of the quality assurance program covers all stages of radionuclide therapy – from patient identification and radiopharmaceutical quality control to the evaluation of therapeutic efficacy and safety at all levels. Particular attention is given to the need for equipment monitoring, imaging parameter control, management of biological waste, patient instruction upon discharge, as well as dosimetry-guided radionuclide therapy planning aimed at optimizing patient radiation protection. The quality assurance program in radionuclide therapy is proposed as a foundation for building a standardized, safe, and effective quality assurance system aligned with international practices, with a primary focus on personalized approaches to the planning and delivery of radionuclide therapy.https://www.radhyg.ru/jour/article/view/1158nuclear medicineradionuclide therapyquality assurancequality assurance programradiation safety
spellingShingle A. V. Likhacheva
A. V. Vodovatov
L. A. Chipiga
Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
Радиационная гигиена
nuclear medicine
radionuclide therapy
quality assurance
quality assurance program
radiation safety
title Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
title_full Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
title_fullStr Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
title_full_unstemmed Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
title_short Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs
title_sort optimization of radiation protection in radionuclide therapy proposals for developing quality assurance programs
topic nuclear medicine
radionuclide therapy
quality assurance
quality assurance program
radiation safety
url https://www.radhyg.ru/jour/article/view/1158
work_keys_str_mv AT avlikhacheva optimizationofradiationprotectioninradionuclidetherapyproposalsfordevelopingqualityassuranceprograms
AT avvodovatov optimizationofradiationprotectioninradionuclidetherapyproposalsfordevelopingqualityassuranceprograms
AT lachipiga optimizationofradiationprotectioninradionuclidetherapyproposalsfordevelopingqualityassuranceprograms