Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway

Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway

IntroductionSperm damage from oxidative stress is common in semen cryopreservation. Natural antioxidants for frozen semen are largely unexplored. Artesunate (ART), derived from Artemisia annua and used for malaria treatment, shows potential as a frozen semen antioxidant.MethodsWe investigated the ef...

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Bibliographic Details
Main Authors: Yilin Fan, Weibing Lv, Xiaowei Li, Geri Wanma, Jian Li, Xianrong Xiong, Xiaoqiang He, Yanwen Wang, Shi Yin, Wei Fu, Honghong He, Yaqiu Lin, Daoliang Lan, Yan Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Veterinary Science
Subjects:
yak sperm
cryopreservation
artesunate
SOD1 protein
antioxidant
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1613506/full
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