MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN

The review outlines the main mechanisms of protective estrogen effects on cardiovascular system and the role of estrogen deficiency in cardiovascular disease (CVD) development. The position of the International Menopause Society (2009) on CVD in women is summarized. The importance of non-pharmaceuti...

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Main Authors: S. N. Tolstov, I. A. Salov, V. B. Mychka, M. Yu. Kirillova, N. A. Voychenko, I. V. Kuznetsova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2011-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1180
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author S. N. Tolstov
I. A. Salov
V. B. Mychka
M. Yu. Kirillova
N. A. Voychenko
I. V. Kuznetsova
author_facet S. N. Tolstov
I. A. Salov
V. B. Mychka
M. Yu. Kirillova
N. A. Voychenko
I. V. Kuznetsova
author_sort S. N. Tolstov
collection DOAJ
description The review outlines the main mechanisms of protective estrogen effects on cardiovascular system and the role of estrogen deficiency in cardiovascular disease (CVD) development. The position of the International Menopause Society (2009) on CVD in women is summarized. The importance of non-pharmaceutical measures in lifestyle modification and CVD risk factor (RF) management is discussed. The main principles of pharmaceutical treatment in premenopausal women are presented, together with the clinical evidence on mildronate in CVD prevention. The specific features of antihypertensive therapy in menopausal women are discussed. The authors justify the use of an angiotensin II receptor antagonist losartan as a first-choice medication for the management of arterial hypertension (AH) and metabolic disturbances. The role of lipid-lowering and glucose-lowering therapy is also demonstrated. Mutual efforts of cardiologists and gynecologists, together with active monitoring, are important components of RF management and primary CVD prevention in women.
format Article
id doaj-art-84f1320cce65436d8bf64b5bfa3d6247
institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2011-12-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-84f1320cce65436d8bf64b5bfa3d62472025-08-20T03:35:11Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202011-12-010698104984MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMENS. N. Tolstov0I. A. Salov1V. B. Mychka2M. Yu. Kirillova3N. A. Voychenko4I. V. Kuznetsova5ГОУ ВПО Саратовский ГМУ Росздрава, СаратовГОУ ВПО Саратовский ГМУ Росздрава, СаратовФГУ Российский кардиологический научно – производственный комплекс Росмедтехнологий, Институт клинической кардиологии им. А. Л. Мясникова – отдел системных гипертензий, МоскваФГУ Российский кардиологический научно – производственный комплекс Росмедтехнологий, Институт клинической кардиологии им. А. Л. Мясникова – отдел системных гипертензий, МоскваПервый Московский государственный медицинский университет имени И. М. Сеченова, МоскваГОУ ДПО Российская медицинская академия последипломного образования Росздрава, МоскваThe review outlines the main mechanisms of protective estrogen effects on cardiovascular system and the role of estrogen deficiency in cardiovascular disease (CVD) development. The position of the International Menopause Society (2009) on CVD in women is summarized. The importance of non-pharmaceutical measures in lifestyle modification and CVD risk factor (RF) management is discussed. The main principles of pharmaceutical treatment in premenopausal women are presented, together with the clinical evidence on mildronate in CVD prevention. The specific features of antihypertensive therapy in menopausal women are discussed. The authors justify the use of an angiotensin II receptor antagonist losartan as a first-choice medication for the management of arterial hypertension (AH) and metabolic disturbances. The role of lipid-lowering and glucose-lowering therapy is also demonstrated. Mutual efforts of cardiologists and gynecologists, together with active monitoring, are important components of RF management and primary CVD prevention in women.https://russjcardiol.elpub.ru/jour/article/view/1180menopauserisk factorsnon-pharmaceutical measuresmildronateantihypertensive therapylosartan
spellingShingle S. N. Tolstov
I. A. Salov
V. B. Mychka
M. Yu. Kirillova
N. A. Voychenko
I. V. Kuznetsova
MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
Российский кардиологический журнал
menopause
risk factors
non-pharmaceutical measures
mildronate
antihypertensive therapy
losartan
title MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
title_full MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
title_fullStr MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
title_full_unstemmed MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
title_short MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
title_sort main therapeutic principles in premenopausal women
topic menopause
risk factors
non-pharmaceutical measures
mildronate
antihypertensive therapy
losartan
url https://russjcardiol.elpub.ru/jour/article/view/1180
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AT iasalov maintherapeuticprinciplesinpremenopausalwomen
AT vbmychka maintherapeuticprinciplesinpremenopausalwomen
AT myukirillova maintherapeuticprinciplesinpremenopausalwomen
AT navoychenko maintherapeuticprinciplesinpremenopausalwomen
AT ivkuznetsova maintherapeuticprinciplesinpremenopausalwomen