Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease
Aim: Behçet's disease (BD) is a systemic immuno-inflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis fa...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350220131935 |
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| _version_ | 1832563926620962816 |
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| author | Cem Evereklioglu Hamdi Er Yusuf Türköz Mustafa Çekmen |
| author_facet | Cem Evereklioglu Hamdi Er Yusuf Türköz Mustafa Çekmen |
| author_sort | Cem Evereklioglu |
| collection | DOAJ |
| description | Aim: Behçet's disease (BD) is a systemic immuno-inflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis factor (TNF)-α, interleukin-1beta (IL-1β), soluble IL-2 receptor (sIL-2R), IL-6, and chemokine IL-8 levels in patients with BD. We also determined the end product of lipid peroxidation (malondialdehyde (MDA)) in BD patients as an index for oxidative stress. |
| format | Article |
| id | doaj-art-84e81671e4b1404cb1c06f55d5e51b3c |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-84e81671e4b1404cb1c06f55d5e51b3c2025-02-03T01:12:12ZengWileyMediators of Inflammation0962-93511466-18612002-01-01112879310.1080/09629350220131935Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's diseaseCem Evereklioglu0Hamdi Er1Yusuf Türköz2Mustafa Çekmen3Department of Ophthalmology, Gaziantep University Medical Faculty, Research Hospital, Gaziantep, TurkeyDepartment of Biochemistry, Inönü University Medical Faculty, Turgut Ozal Medical Centre, Research Hospital, Malatya, TurkeyDepartment of Biochemistry, Inönü University Medical Faculty, Turgut Ozal Medical Centre, Research Hospital, Malatya, TurkeyDepartment of Ophthalmology, Gaziantep University Medical Faculty, Research Hospital, Gaziantep, TurkeyAim: Behçet's disease (BD) is a systemic immuno-inflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis factor (TNF)-α, interleukin-1beta (IL-1β), soluble IL-2 receptor (sIL-2R), IL-6, and chemokine IL-8 levels in patients with BD. We also determined the end product of lipid peroxidation (malondialdehyde (MDA)) in BD patients as an index for oxidative stress.http://dx.doi.org/10.1080/09629350220131935 |
| spellingShingle | Cem Evereklioglu Hamdi Er Yusuf Türköz Mustafa Çekmen Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease Mediators of Inflammation |
| title | Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated
with elevated lipid peroxidation in patients with Behçet's disease |
| title_full | Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated
with elevated lipid peroxidation in patients with Behçet's disease |
| title_fullStr | Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated
with elevated lipid peroxidation in patients with Behçet's disease |
| title_full_unstemmed | Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated
with elevated lipid peroxidation in patients with Behçet's disease |
| title_short | Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated
with elevated lipid peroxidation in patients with Behçet's disease |
| title_sort | serum levels of tnf α sil 2r il 6 and il 8 are increased and associated with elevated lipid peroxidation in patients with behcet s disease |
| url | http://dx.doi.org/10.1080/09629350220131935 |
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