Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), whi...
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| Format: | Article |
| Language: | zho |
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The Editorial Department of Chinese Journal of Clinical Research
2024-11-01
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| Series: | Zhongguo linchuang yanjiu |
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| Online Access: | http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105 |
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| _version_ | 1850127826595872768 |
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| author | ZHANG Jun, FENG Jianhong, DU Xianrong |
| author_facet | ZHANG Jun, FENG Jianhong, DU Xianrong |
| author_sort | ZHANG Jun, FENG Jianhong, DU Xianrong |
| collection | DOAJ |
| description | Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), which is the dual effect of coagulation cascade reaction and inflammatory immune response. This paper describes the molecular mechanism and the latest treatment research progress of DIC in sepsis, in order to provide new ideas and methods for clinical work.
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| format | Article |
| id | doaj-art-84e6da91ef1241ae8639e940fe97ba0a |
| institution | OA Journals |
| issn | 1674-8182 |
| language | zho |
| publishDate | 2024-11-01 |
| publisher | The Editorial Department of Chinese Journal of Clinical Research |
| record_format | Article |
| series | Zhongguo linchuang yanjiu |
| spelling | doaj-art-84e6da91ef1241ae8639e940fe97ba0a2025-08-20T02:33:34ZzhoThe Editorial Department of Chinese Journal of Clinical ResearchZhongguo linchuang yanjiu1674-81822024-11-0137111669167310.13429/j.cnki.cjcr.2024.11.038Mechanism and treatment progress of disseminated intravascular coagulation in sepsisZHANG Jun, FENG Jianhong, DU Xianrong 0Department of Emergency Medicine, Shanxi Provincial People's Hospital, The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, Shanxi 030012, ChinaSepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), which is the dual effect of coagulation cascade reaction and inflammatory immune response. This paper describes the molecular mechanism and the latest treatment research progress of DIC in sepsis, in order to provide new ideas and methods for clinical work. http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap |
| spellingShingle | ZHANG Jun, FENG Jianhong, DU Xianrong Mechanism and treatment progress of disseminated intravascular coagulation in sepsis Zhongguo linchuang yanjiu sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap |
| title | Mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| title_full | Mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| title_fullStr | Mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| title_full_unstemmed | Mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| title_short | Mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| title_sort | mechanism and treatment progress of disseminated intravascular coagulation in sepsis |
| topic | sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap |
| url | http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105 |
| work_keys_str_mv | AT zhangjunfengjianhongduxianrong mechanismandtreatmentprogressofdisseminatedintravascularcoagulationinsepsis |