Mechanism and treatment progress of disseminated intravascular coagulation in sepsis

Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), whi...

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Main Author: ZHANG Jun, FENG Jianhong, DU Xianrong
Format: Article
Language:zho
Published: The Editorial Department of Chinese Journal of Clinical Research 2024-11-01
Series:Zhongguo linchuang yanjiu
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Online Access:http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105
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author ZHANG Jun, FENG Jianhong, DU Xianrong
author_facet ZHANG Jun, FENG Jianhong, DU Xianrong
author_sort ZHANG Jun, FENG Jianhong, DU Xianrong
collection DOAJ
description Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), which is the dual effect of coagulation cascade reaction and inflammatory immune response. This paper describes the molecular mechanism and the latest treatment research progress of DIC in sepsis, in order to provide new ideas and methods for clinical work.
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publisher The Editorial Department of Chinese Journal of Clinical Research
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spelling doaj-art-84e6da91ef1241ae8639e940fe97ba0a2025-08-20T02:33:34ZzhoThe Editorial Department of Chinese Journal of Clinical ResearchZhongguo linchuang yanjiu1674-81822024-11-0137111669167310.13429/j.cnki.cjcr.2024.11.038Mechanism and treatment progress of disseminated intravascular coagulation in sepsisZHANG Jun, FENG Jianhong, DU Xianrong 0Department of Emergency Medicine, Shanxi Provincial People's Hospital, The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, Shanxi 030012, ChinaSepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), which is the dual effect of coagulation cascade reaction and inflammatory immune response. This paper describes the molecular mechanism and the latest treatment research progress of DIC in sepsis, in order to provide new ideas and methods for clinical work. http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap
spellingShingle ZHANG Jun, FENG Jianhong, DU Xianrong
Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
Zhongguo linchuang yanjiu
sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap
title Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
title_full Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
title_fullStr Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
title_full_unstemmed Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
title_short Mechanism and treatment progress of disseminated intravascular coagulation in sepsis
title_sort mechanism and treatment progress of disseminated intravascular coagulation in sepsis
topic sepsis, coagulation system, disseminated intravascular coagulation, tissue factor, neutrophil extracellular trap
url http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105
work_keys_str_mv AT zhangjunfengjianhongduxianrong mechanismandtreatmentprogressofdisseminatedintravascularcoagulationinsepsis