Characterization of sleep apnea among a sample of adults from Samoa

Sleep apnea is a global public health concern, but little research has examined this issue in low- and middle-income countries, including Samoa. The purpose of this study was to examine the sample prevalence and characteristics of sleep apnea using a validated home sleep apnea device (WatchPAT, Itam...

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Main Authors: Lacey W. Heinsberg, Alysa Pomer, Brian E. Cade, Jenna C. Carlson, Take Naseri, Muagututia Sefuiva Reupena, Satupa'itea Viali, Daniel E. Weeks, Stephen T. McGarvey, Susan Redline, Nicola L. Hawley
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Sleep Epidemiology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667343624000258
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author Lacey W. Heinsberg
Alysa Pomer
Brian E. Cade
Jenna C. Carlson
Take Naseri
Muagututia Sefuiva Reupena
Satupa'itea Viali
Daniel E. Weeks
Stephen T. McGarvey
Susan Redline
Nicola L. Hawley
author_facet Lacey W. Heinsberg
Alysa Pomer
Brian E. Cade
Jenna C. Carlson
Take Naseri
Muagututia Sefuiva Reupena
Satupa'itea Viali
Daniel E. Weeks
Stephen T. McGarvey
Susan Redline
Nicola L. Hawley
author_sort Lacey W. Heinsberg
collection DOAJ
description Sleep apnea is a global public health concern, but little research has examined this issue in low- and middle-income countries, including Samoa. The purpose of this study was to examine the sample prevalence and characteristics of sleep apnea using a validated home sleep apnea device (WatchPAT, Itamar) and explore factors that may influence sleep health in the Samoan setting. This study used data collected through the Soifua Manuia (“Good Health”) study, which investigated the impact of the body mass index (BMI)-associated genetic variant rs373863828 in CREBRF on metabolic traits in Samoan adults (sampled to overrepresent the obesity-risk allele of interest). A total of 330 participants had sleep data available. Participants (53.3 % female) had a mean (SD) age of 52.0 (9.9) years and BMI of 35.5 (7.5) kg/m2, and 36.3 % of the sample had type 2 diabetes. Based on the 3 % and 4 % apnea hypopnea indices (AHI) and the 4 % oxygen desaturation index (ODI), descriptive analyses revealed moderate to severe sleep apnea (defined as ≥15 events/hr) in 54.9 %, 31.5 %, and 34.5 % of the sample, respectively. Sleep apnea was more severe in men (e.g., AHI 3 % ≥15 in 61.7 % of men and 48.9 % of women). Correction for non-representational sampling related to the CREBRF obesity-risk allele resulted in only slightly lower estimates. Multiple linear regression linked a higher number of events/hr to higher age, male sex, higher BMI, higher abdominal-hip circumference ratio, and geographic region of residence. Further research and an increased focus on equitable and affordable diagnosis and access to treatment are crucial to addressing sleep apnea in Samoa and globally.
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spelling doaj-art-84e041f31fcd45bba3efe0ad5f8eff7a2025-08-20T02:34:19ZengElsevierSleep Epidemiology2667-34362024-12-01410009910.1016/j.sleepe.2024.100099Characterization of sleep apnea among a sample of adults from SamoaLacey W. Heinsberg0Alysa Pomer1Brian E. Cade2Jenna C. Carlson3Take Naseri4Muagututia Sefuiva Reupena5Satupa'itea Viali6Daniel E. Weeks7Stephen T. McGarvey8Susan Redline9Nicola L. Hawley10Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Corresponding author at: Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, 440 Victoria Building, 3500 Victoria Street, Pittsburgh, PA 15261, USA.Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USADivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USADepartment of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USAMinistry of Health, Apia, SamoaLutia i Puava Ae Mapu i Fagalele, Apia, SamoaSchool of Medicine, National University of Samoa, Apia, SamoaDepartment of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USAInternational Health Institute and Department of Epidemiology, School of Public Health, and Department of Anthropology, Brown University, Providence, RI, USADivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USADepartment of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, CT, USASleep apnea is a global public health concern, but little research has examined this issue in low- and middle-income countries, including Samoa. The purpose of this study was to examine the sample prevalence and characteristics of sleep apnea using a validated home sleep apnea device (WatchPAT, Itamar) and explore factors that may influence sleep health in the Samoan setting. This study used data collected through the Soifua Manuia (“Good Health”) study, which investigated the impact of the body mass index (BMI)-associated genetic variant rs373863828 in CREBRF on metabolic traits in Samoan adults (sampled to overrepresent the obesity-risk allele of interest). A total of 330 participants had sleep data available. Participants (53.3 % female) had a mean (SD) age of 52.0 (9.9) years and BMI of 35.5 (7.5) kg/m2, and 36.3 % of the sample had type 2 diabetes. Based on the 3 % and 4 % apnea hypopnea indices (AHI) and the 4 % oxygen desaturation index (ODI), descriptive analyses revealed moderate to severe sleep apnea (defined as ≥15 events/hr) in 54.9 %, 31.5 %, and 34.5 % of the sample, respectively. Sleep apnea was more severe in men (e.g., AHI 3 % ≥15 in 61.7 % of men and 48.9 % of women). Correction for non-representational sampling related to the CREBRF obesity-risk allele resulted in only slightly lower estimates. Multiple linear regression linked a higher number of events/hr to higher age, male sex, higher BMI, higher abdominal-hip circumference ratio, and geographic region of residence. Further research and an increased focus on equitable and affordable diagnosis and access to treatment are crucial to addressing sleep apnea in Samoa and globally.http://www.sciencedirect.com/science/article/pii/S2667343624000258Sleep apneaPacific islanderSleep healthSleep epidemiology
spellingShingle Lacey W. Heinsberg
Alysa Pomer
Brian E. Cade
Jenna C. Carlson
Take Naseri
Muagututia Sefuiva Reupena
Satupa'itea Viali
Daniel E. Weeks
Stephen T. McGarvey
Susan Redline
Nicola L. Hawley
Characterization of sleep apnea among a sample of adults from Samoa
Sleep Epidemiology
Sleep apnea
Pacific islander
Sleep health
Sleep epidemiology
title Characterization of sleep apnea among a sample of adults from Samoa
title_full Characterization of sleep apnea among a sample of adults from Samoa
title_fullStr Characterization of sleep apnea among a sample of adults from Samoa
title_full_unstemmed Characterization of sleep apnea among a sample of adults from Samoa
title_short Characterization of sleep apnea among a sample of adults from Samoa
title_sort characterization of sleep apnea among a sample of adults from samoa
topic Sleep apnea
Pacific islander
Sleep health
Sleep epidemiology
url http://www.sciencedirect.com/science/article/pii/S2667343624000258
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