S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice

S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice

BackgroundBrachial plexus root avulsion (BPRA) often occurs in high-speed traffic accidents or shoulder dystocia, resulting in motor dysfunction. S-ketamine, a clinical anesthetic and antidepressant drug, is an NMDA receptor antagonist that may be effective against glutamate excitotoxicity after ner...

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Bibliographic Details
Main Authors: Ronghua Huang, Bingbiao Lin, Lingtai Yu, Qichen Luo, Hongyan Tian, Chenrui Li, Naili Wei, Shaohui Zhuang, Jian Chen, Yalan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
S-ketamine
brachial plexus root avulsion
motor function
recovery
BDNF
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1630158/full
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