Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources

Cancer is known as the main cause of mortality in the world, and every year, the rate of incidence and death due to cancer is increasing. Bioactive peptides are one of the novel therapeutic options that are considered a suitable alternative to toxic chemotherapy drugs because they limit side effects...

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Main Authors: Maryam Bidram, Mohamad Reza Ganjalikhany
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024165942
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author Maryam Bidram
Mohamad Reza Ganjalikhany
author_facet Maryam Bidram
Mohamad Reza Ganjalikhany
author_sort Maryam Bidram
collection DOAJ
description Cancer is known as the main cause of mortality in the world, and every year, the rate of incidence and death due to cancer is increasing. Bioactive peptides are one of the novel therapeutic options that are considered a suitable alternative to toxic chemotherapy drugs because they limit side effects with their specific function. In fact, bioactive peptides are short amino acid sequences that obtain diverse physiological functions to maintain human health after being released from parent proteins. This group of biological molecules that can be isolated from different types of natural protein sources has attracted much attention in the field of pharmaceutical and functional foods production. The current article describes the therapeutic benefits of bioactive peptides and specifically and extensively reviews their role in cancer treatment, available sources for discovering anticancer peptides, mechanisms of action, production methods, and existing challenges.
format Article
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publishDate 2024-12-01
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series Heliyon
spelling doaj-art-84d9757ba87a4ecf8f73e08a4550d4a02025-08-20T02:38:21ZengElsevierHeliyon2405-84402024-12-011023e4056310.1016/j.heliyon.2024.e40563Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resourcesMaryam Bidram0Mohamad Reza Ganjalikhany1Department of Cell and Molecular Biology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, IranCorresponding author.; Department of Cell and Molecular Biology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, IranCancer is known as the main cause of mortality in the world, and every year, the rate of incidence and death due to cancer is increasing. Bioactive peptides are one of the novel therapeutic options that are considered a suitable alternative to toxic chemotherapy drugs because they limit side effects with their specific function. In fact, bioactive peptides are short amino acid sequences that obtain diverse physiological functions to maintain human health after being released from parent proteins. This group of biological molecules that can be isolated from different types of natural protein sources has attracted much attention in the field of pharmaceutical and functional foods production. The current article describes the therapeutic benefits of bioactive peptides and specifically and extensively reviews their role in cancer treatment, available sources for discovering anticancer peptides, mechanisms of action, production methods, and existing challenges.http://www.sciencedirect.com/science/article/pii/S2405844024165942Bioactive peptidesCancerTherapeutic applicationsAnticancer peptidesFunctional foodsNatural resources
spellingShingle Maryam Bidram
Mohamad Reza Ganjalikhany
Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
Heliyon
Bioactive peptides
Cancer
Therapeutic applications
Anticancer peptides
Functional foods
Natural resources
title Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
title_full Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
title_fullStr Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
title_full_unstemmed Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
title_short Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
title_sort bioactive peptides from food science to pharmaceutical industries their mechanism of action potential role in cancer treatment and available resources
topic Bioactive peptides
Cancer
Therapeutic applications
Anticancer peptides
Functional foods
Natural resources
url http://www.sciencedirect.com/science/article/pii/S2405844024165942
work_keys_str_mv AT maryambidram bioactivepeptidesfromfoodsciencetopharmaceuticalindustriestheirmechanismofactionpotentialroleincancertreatmentandavailableresources
AT mohamadrezaganjalikhany bioactivepeptidesfromfoodsciencetopharmaceuticalindustriestheirmechanismofactionpotentialroleincancertreatmentandavailableresources