ThermOptCobra: Thermodynamically optimal construction and analysis of metabolic networks for reliable phenotype predictions
Summary: Reliable genome-scale metabolic models (GEMs) of metabolic processes are important for understanding cellular behavior. However, the presence of thermodynamically infeasible cycles (TICs) limits their predictive ability. We present ThermOptCOBRA, a comprehensive solution consisting of four...
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| Main Authors: | Pavan Kumar S, Nirav Pravinbhai Bhatt |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225012660 |
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