Investigating the potential of oxidative stress-related gene as predictive markers in idiopathic pulmonary fibrosis

Investigating the potential of oxidative stress-related gene as predictive markers in idiopathic pulmonary fibrosis

Abstract This study investigates genes linking oxidative stress to idiopathic pulmonary fibrosis (IPF) through multi-omics data integration. We collected oxidative stress-related genes from GeneCards and integrated data for gene expression (eQTLs), DNA methylation (mQTLs), and protein expression (pQ...

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Bibliographic Details
Main Authors: Yuhao Wang, Zhao Zhang, Hongnan Zhang, Luyao Xu, Shuling Huang, Ying Wen, Zhiming Zhuang, Xiaoxin Li, Jinyi Lu, Xudong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Oxidative stress
Idiopathic pulmonary fibrosis
Multi-omics
Mendelian randomization analysis
Colocalization analysis
Online Access:https://doi.org/10.1038/s41598-025-02579-7
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