NR4A3 potentials M1-like macrophage polarization to facilitate anti-tumor immune responses in breast cancer
Abstract Breast cancer (BC) is commonly labeled a “cold tumor” due to its dense population of immunosuppressive cells, particularly M2-like macrophages, which contribute to its resistance to therapy. Thus, there is a pressing need to shift the macrophage polarization towards M1 and revitalize the tu...
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| Main Authors: | Yi-yu Qian, Ning Jin, Shan-shan Rao, Ya Wang, Xin Li, Wen Pan, Pu Huang, Si-yuan Wang, Ping-fei Li, Yan-kai Lv, Qing-lei Gao, Yu Xia |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | npj Breast Cancer |
| Online Access: | https://doi.org/10.1038/s41523-025-00785-0 |
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