NR4A3 potentials M1-like macrophage polarization to facilitate anti-tumor immune responses in breast cancer

Abstract Breast cancer (BC) is commonly labeled a “cold tumor” due to its dense population of immunosuppressive cells, particularly M2-like macrophages, which contribute to its resistance to therapy. Thus, there is a pressing need to shift the macrophage polarization towards M1 and revitalize the tu...

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Bibliographic Details
Main Authors: Yi-yu Qian, Ning Jin, Shan-shan Rao, Ya Wang, Xin Li, Wen Pan, Pu Huang, Si-yuan Wang, Ping-fei Li, Yan-kai Lv, Qing-lei Gao, Yu Xia
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00785-0
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