Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023)
**Background:** Infections attributable to respiratory syncytial virus (RSV) are a major cause of hospitalization among young children worldwide. Despite substantial clinical and economic burden, real-world data associated with RSV infections in the United Arab Emirates (UAE) are limited. **Objectiv...
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| Format: | Article |
| Language: | English |
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Columbia Data Analytics, LLC
2024-11-01
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| Series: | Journal of Health Economics and Outcomes Research |
| Online Access: | https://doi.org/10.36469/001c.123889 |
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| author | Jean Joury Nawal Al Kaabi Sara Al Dallal Bassam Mahboub Mostafa Zayed Mohamed Abdelaziz Jennifer Onwumeh-Okwundu Mark A. Fletcher Subramanyam Kumaresan Badarinath C. Ramachandrachar Mohamed Farghaly |
| author_facet | Jean Joury Nawal Al Kaabi Sara Al Dallal Bassam Mahboub Mostafa Zayed Mohamed Abdelaziz Jennifer Onwumeh-Okwundu Mark A. Fletcher Subramanyam Kumaresan Badarinath C. Ramachandrachar Mohamed Farghaly |
| author_sort | Jean Joury |
| collection | DOAJ |
| description | **Background:** Infections attributable to respiratory syncytial virus (RSV) are a major cause of hospitalization among young children worldwide. Despite substantial clinical and economic burden, real-world data associated with RSV infections in the United Arab Emirates (UAE) are limited.
**Objectives:** This study aimed to assess among children (<18 years) diagnosed with RSV the epidemiology, seasonality, comorbidities, treatment patterns, length of hospital stay, healthcare resource utilization (HCRU), and costs associated with pediatric infection in Dubai, UAE.
**Methods:** This 10-year retrospective cohort study (Jan. 1, 2014–Sept. 30, 2023) utilized Dubai Real-World Database, a private insurance claims database. Patients aged <18 years with a first-episode diagnosis claim (primary or secondary, or a hospital admission) for RSV any time during the index period (Jan. 1, 2014–June 30, 2023) were included. Outcomes were analyzed during a 3-month follow-up. Patients were stratified into 3 cohorts: Cohort 1 (<2 years), Cohort 2 (2 to <6 years), and Cohort 3 (6 to <18 years).
**Results:** Of 28 011 patients identified, 25 729 were aged <18 years with RSV infection. An increasing trend in reported cases was observed from 2014 to 2022, with an average annual increase of 55%. Half of study patients (49.3%) belonged to Cohort 1, with a mean age of 0.6 years, while less than 2% had known risk factors and 22% of the patients in cohort 1 were hospitalized. In Cohort 1, 32.0% had upper respiratory tract infections, 39.4% had lower respiratory tract infections, and 44.4% of patients had an “other respiratory disease.” The average length of hospitalization was about 4 days across all cohorts. The total hospitalization cost was highest in patients <2 years, amounting to US $9 798 174 (median, US $2241.30).
**Conclusion:** Among the RSV patients, 49.3% were <2 years of age and few had recognized risk factors. Among patients <2 years, 22% were hospitalized, with an average hospital stay of 4 days; the cost of hospitalization totaled US $9 798 174. These findings can inform healthcare stakeholders about future policy measures and the need for effective preventive strategies. |
| format | Article |
| id | doaj-art-84cafb89b1744634800aad5def791c1d |
| institution | Kabale University |
| issn | 2327-2236 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Columbia Data Analytics, LLC |
| record_format | Article |
| series | Journal of Health Economics and Outcomes Research |
| spelling | doaj-art-84cafb89b1744634800aad5def791c1d2025-02-10T16:12:36ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362024-11-01112Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023)Jean JouryNawal Al KaabiSara Al DallalBassam MahboubMostafa ZayedMohamed AbdelazizJennifer Onwumeh-OkwunduMark A. FletcherSubramanyam KumaresanBadarinath C. RamachandracharMohamed Farghaly**Background:** Infections attributable to respiratory syncytial virus (RSV) are a major cause of hospitalization among young children worldwide. Despite substantial clinical and economic burden, real-world data associated with RSV infections in the United Arab Emirates (UAE) are limited. **Objectives:** This study aimed to assess among children (<18 years) diagnosed with RSV the epidemiology, seasonality, comorbidities, treatment patterns, length of hospital stay, healthcare resource utilization (HCRU), and costs associated with pediatric infection in Dubai, UAE. **Methods:** This 10-year retrospective cohort study (Jan. 1, 2014–Sept. 30, 2023) utilized Dubai Real-World Database, a private insurance claims database. Patients aged <18 years with a first-episode diagnosis claim (primary or secondary, or a hospital admission) for RSV any time during the index period (Jan. 1, 2014–June 30, 2023) were included. Outcomes were analyzed during a 3-month follow-up. Patients were stratified into 3 cohorts: Cohort 1 (<2 years), Cohort 2 (2 to <6 years), and Cohort 3 (6 to <18 years). **Results:** Of 28 011 patients identified, 25 729 were aged <18 years with RSV infection. An increasing trend in reported cases was observed from 2014 to 2022, with an average annual increase of 55%. Half of study patients (49.3%) belonged to Cohort 1, with a mean age of 0.6 years, while less than 2% had known risk factors and 22% of the patients in cohort 1 were hospitalized. In Cohort 1, 32.0% had upper respiratory tract infections, 39.4% had lower respiratory tract infections, and 44.4% of patients had an “other respiratory disease.” The average length of hospitalization was about 4 days across all cohorts. The total hospitalization cost was highest in patients <2 years, amounting to US $9 798 174 (median, US $2241.30). **Conclusion:** Among the RSV patients, 49.3% were <2 years of age and few had recognized risk factors. Among patients <2 years, 22% were hospitalized, with an average hospital stay of 4 days; the cost of hospitalization totaled US $9 798 174. These findings can inform healthcare stakeholders about future policy measures and the need for effective preventive strategies.https://doi.org/10.36469/001c.123889 |
| spellingShingle | Jean Joury Nawal Al Kaabi Sara Al Dallal Bassam Mahboub Mostafa Zayed Mohamed Abdelaziz Jennifer Onwumeh-Okwundu Mark A. Fletcher Subramanyam Kumaresan Badarinath C. Ramachandrachar Mohamed Farghaly Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) Journal of Health Economics and Outcomes Research |
| title | Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) |
| title_full | Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) |
| title_fullStr | Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) |
| title_full_unstemmed | Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) |
| title_short | Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) |
| title_sort | retrospective analysis of rsv infection in pediatric patients epidemiology comorbidities treatment and costs in dubai 2014 2023 |
| url | https://doi.org/10.36469/001c.123889 |
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