Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

BackgroundThe airway epithelial barrier is the first defence against aeroallergens. Nasal epithelial cells (NECs) are vital in regulating innate and adaptive mucosal immunity in allergic rhinitis (AR). Tregs produce cytokines essential for the immunomodulatory activities in allergen immunotherapy. U...

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Bibliographic Details
Main Authors: Jichao Sha, Maolin Yang, Yashu Lei, Liwei Sun, Cuida Meng, Dongdong Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
allergic rhinitis
nasal epithelial cells
regulatory T cells
cytokines
CC chemokine ligand 1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526081/full
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