SHengXIaN-QuYu DEcoction in the Treatment of Heart Failure with Reduced and Mildly-Reduced Ejection Fraction (SHINE-HF): rationale and design for a multicenter randomized controlled trial

SHengXIaN-QuYu DEcoction in the Treatment of Heart Failure with Reduced and Mildly-Reduced Ejection Fraction (SHINE-HF): rationale and design for a multicenter randomized controlled trial

Background: Although contemporary guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) and heart failure with mildly-reduced ejection fraction (HFmrEF) has been shown to significantly improve prognosis, patients with these conditions still face cons...

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Main Authors: Lina Feng, Sizhen Chen, Jiang Liu, Chunyan Li, Hongshuai Cao, Liyuan Tao, Fang Fang, Feijiao Huo, Lingling Liu, Palidan Wubu'er, Ming Wang, Xiaohua Zhao, Xiaojian Liu, Hui Xin, Ding Li, Weisheng Mao, Liang Gui, Jianfei Guan, Zhiyang Zhu, Haijun Song, Shi Li, Yingjing Song, Meiling Shi, Chao Zhang, Zhiying Zhang, Huiyun Li, Xiaobin Wang, Baolong Yang, Zhao Jin, Yifei Du, Yonghui Gao, Lulei Cao, Jiamei Yang, Qiao Wang, Naidan Kang, Lina Su, Zhaoqi Zheng, Jiasai Fan, Jiaying Xu, Zaixiang Shi, Jingyi Ren
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Contemporary Clinical Trials Communications
Subjects:
Heart failure with reduced and mildly-reduced ejection fraction
Complementary and alternative medicine
Traditional Chinese medicine
ShengXian-QuYu decoction
Kansas city cardiomyopathy questionnaire
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865425000717
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