Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation
Triple primary malignancies are rare, involving the occurrence of three distinct, unrelated cancers in a single patient, requiring a personalized, multidisciplinary treatment approach. A 69-year-old male was diagnosed with dermatofibrosarcoma protuberans (DFSP), lung adenocarcinoma, and papillary th...
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| Language: | English |
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Elsevier
2025-02-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324012986 |
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| author | Luan Minh Bao Tran Minh Duc Do Truong Hung Nguyen Ngoc-Minh Vuong |
| author_facet | Luan Minh Bao Tran Minh Duc Do Truong Hung Nguyen Ngoc-Minh Vuong |
| author_sort | Luan Minh Bao Tran |
| collection | DOAJ |
| description | Triple primary malignancies are rare, involving the occurrence of three distinct, unrelated cancers in a single patient, requiring a personalized, multidisciplinary treatment approach. A 69-year-old male was diagnosed with dermatofibrosarcoma protuberans (DFSP), lung adenocarcinoma, and papillary thyroid carcinoma. After amputation for DFSP, following staging and genetic evaluation, a multidisciplinary tumor board designed a tailored treatment plan, adjuvant chemotherapy for lung adenocarcinoma while monitor regularly the thyroid carcinoma via ultrasound. This case highlights the extreme rarity of this triple primary cancers combination and emphasizes the need for individualized treatment planning. Each cancer's unique characteristics, prognosis, and potential interactions must be considered, alongside the patient's overall health and treatment tolerability, to optimize outcomes in such complex cases. |
| format | Article |
| id | doaj-art-84aa9c77dd8b4a7b91dd6df6526eb0f6 |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-84aa9c77dd8b4a7b91dd6df6526eb0f62025-08-20T02:37:03ZengElsevierRadiology Case Reports1930-04332025-02-012021194119910.1016/j.radcr.2024.11.031Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluationLuan Minh Bao Tran0Minh Duc Do1Truong Hung Nguyen2Ngoc-Minh Vuong3Thoracic and Cardiovascular Surgery Department, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam; Department of Thoracic and Vascular Surgery, University Medical Center Ho Chi Minh City, Ho Chi Minh, VietnamCenter for Molecular Biomedicine, University of Medicine and Pharmacy at Ho Chi Minh CityThoracic and Cardiovascular Surgery Department, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam; Department of Adult Cardiac Surgery, University Medical Center Ho Chi Minh City, Ho Chi Minh, VietnamDepartment of Adult Cardiac Surgery, University Medical Center Ho Chi Minh City, Ho Chi Minh, Vietnam; Corresponding author.Triple primary malignancies are rare, involving the occurrence of three distinct, unrelated cancers in a single patient, requiring a personalized, multidisciplinary treatment approach. A 69-year-old male was diagnosed with dermatofibrosarcoma protuberans (DFSP), lung adenocarcinoma, and papillary thyroid carcinoma. After amputation for DFSP, following staging and genetic evaluation, a multidisciplinary tumor board designed a tailored treatment plan, adjuvant chemotherapy for lung adenocarcinoma while monitor regularly the thyroid carcinoma via ultrasound. This case highlights the extreme rarity of this triple primary cancers combination and emphasizes the need for individualized treatment planning. Each cancer's unique characteristics, prognosis, and potential interactions must be considered, alongside the patient's overall health and treatment tolerability, to optimize outcomes in such complex cases.http://www.sciencedirect.com/science/article/pii/S1930043324012986Triple primary malignanciesRadiology in cancer diagnosisMultimodal cancer treatmentHistopathology in triple malignanciesRare cancer association |
| spellingShingle | Luan Minh Bao Tran Minh Duc Do Truong Hung Nguyen Ngoc-Minh Vuong Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation Radiology Case Reports Triple primary malignancies Radiology in cancer diagnosis Multimodal cancer treatment Histopathology in triple malignancies Rare cancer association |
| title | Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| title_full | Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| title_fullStr | Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| title_full_unstemmed | Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| title_short | Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| title_sort | rare occurrence of triple primary malignant tumors dermatofibrosarcoma protuberans lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation |
| topic | Triple primary malignancies Radiology in cancer diagnosis Multimodal cancer treatment Histopathology in triple malignancies Rare cancer association |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324012986 |
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