Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study

Abstract While conventional spirometry is associated with strenuous “forced” maximal respiratory maneuvers and infection control implications, oscillometry is not associated with these issues. However, portability, convenience of use, and interpretation remain common limitations to both techniques....

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Main Authors: Felix‐Antoine Coutu, Dany Malaeb, Olivia C. Iorio, Seyedfakhreddin Nabavi, Tom McFarland, Lennart K. A. Lundblad, Ron J. Dandurand, Stewart B. Gottfried, Bryan A. Ross
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Physiological Reports
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Online Access:https://doi.org/10.14814/phy2.70307
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author Felix‐Antoine Coutu
Dany Malaeb
Olivia C. Iorio
Seyedfakhreddin Nabavi
Tom McFarland
Lennart K. A. Lundblad
Ron J. Dandurand
Stewart B. Gottfried
Bryan A. Ross
author_facet Felix‐Antoine Coutu
Dany Malaeb
Olivia C. Iorio
Seyedfakhreddin Nabavi
Tom McFarland
Lennart K. A. Lundblad
Ron J. Dandurand
Stewart B. Gottfried
Bryan A. Ross
author_sort Felix‐Antoine Coutu
collection DOAJ
description Abstract While conventional spirometry is associated with strenuous “forced” maximal respiratory maneuvers and infection control implications, oscillometry is not associated with these issues. However, portability, convenience of use, and interpretation remain common limitations to both techniques. This study tested the concordance and agreement between resistance measurements obtained from the handheld portable REOM device (Reo‐f, Reo‐s) with those from conventional oscillometry (R19, R5) in PFT‐confirmed “mild” (GOLD 1) and “very severe” (GOLD 4) COPD. Unadjusted and adjusted concordance (Spearman correlation) and agreement (Bland–Altman tests) served as co‐primary outcomes. Discrimination between GOLD 1 and 4 COPD (Wilcoxon rank sum test, Support Vector Machine (SVM) classifier) and patient user experience (System Utility Scale (SUS), Participant Satisfaction Survey (PSS)) served as secondary outcomes. In 17 participants (GOLD 1 n = 9, GOLD 4 n = 8), adjusted R5‐Reo‐s (0.95 [0.81, 0.98]) and R19‐Reo‐f (0.93 [0.79, 0.99]) correlations were very strong, as was agreement (mean differences: −0.07, 0.08, respectively). Statistically significant between‐group differences were observed for all four resistance parameters. Reo‐s in particular exhibited perfect discrimination between GOLD 1 and 4 disease, with some minor misclassification by Reo‐f, R5 (n = 1 each) and R19 (n = 4). User experience scores were excellent. These results support the capacity for REOM as a novel, complementary diagnostic device in COPD.
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spelling doaj-art-849e8a52a86f4130b903b5a6a3a9c9722025-08-20T03:10:39ZengWileyPhysiological Reports2051-817X2025-04-01137n/an/a10.14814/phy2.70307Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional studyFelix‐Antoine Coutu0Dany Malaeb1Olivia C. Iorio2Seyedfakhreddin Nabavi3Tom McFarland4Lennart K. A. Lundblad5Ron J. Dandurand6Stewart B. Gottfried7Bryan A. Ross8Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaMeakins‐Christie Laboratories, McGill University Montreal Quebec CanadaDepartment of Medicine McGill University Montreal Quebec CanadaDepartment of Medicine McGill University Montreal Quebec CanadaRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation Research Institute of the McGill University Health Centre Montreal Quebec CanadaAbstract While conventional spirometry is associated with strenuous “forced” maximal respiratory maneuvers and infection control implications, oscillometry is not associated with these issues. However, portability, convenience of use, and interpretation remain common limitations to both techniques. This study tested the concordance and agreement between resistance measurements obtained from the handheld portable REOM device (Reo‐f, Reo‐s) with those from conventional oscillometry (R19, R5) in PFT‐confirmed “mild” (GOLD 1) and “very severe” (GOLD 4) COPD. Unadjusted and adjusted concordance (Spearman correlation) and agreement (Bland–Altman tests) served as co‐primary outcomes. Discrimination between GOLD 1 and 4 COPD (Wilcoxon rank sum test, Support Vector Machine (SVM) classifier) and patient user experience (System Utility Scale (SUS), Participant Satisfaction Survey (PSS)) served as secondary outcomes. In 17 participants (GOLD 1 n = 9, GOLD 4 n = 8), adjusted R5‐Reo‐s (0.95 [0.81, 0.98]) and R19‐Reo‐f (0.93 [0.79, 0.99]) correlations were very strong, as was agreement (mean differences: −0.07, 0.08, respectively). Statistically significant between‐group differences were observed for all four resistance parameters. Reo‐s in particular exhibited perfect discrimination between GOLD 1 and 4 disease, with some minor misclassification by Reo‐f, R5 (n = 1 each) and R19 (n = 4). User experience scores were excellent. These results support the capacity for REOM as a novel, complementary diagnostic device in COPD.https://doi.org/10.14814/phy2.70307chronic obstructive pulmonary disease (COPD)handheld portable deviceinterrupter techniqueoscillometryrespiratory resistance
spellingShingle Felix‐Antoine Coutu
Dany Malaeb
Olivia C. Iorio
Seyedfakhreddin Nabavi
Tom McFarland
Lennart K. A. Lundblad
Ron J. Dandurand
Stewart B. Gottfried
Bryan A. Ross
Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
Physiological Reports
chronic obstructive pulmonary disease (COPD)
handheld portable device
interrupter technique
oscillometry
respiratory resistance
title Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
title_full Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
title_fullStr Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
title_full_unstemmed Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
title_short Measuring lung mechanics in patients with COPD using the handheld portable rapid expiratory occlusion monitor (REOM): A cross‐sectional study
title_sort measuring lung mechanics in patients with copd using the handheld portable rapid expiratory occlusion monitor reom a cross sectional study
topic chronic obstructive pulmonary disease (COPD)
handheld portable device
interrupter technique
oscillometry
respiratory resistance
url https://doi.org/10.14814/phy2.70307
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