Are COVID-19 pneumonia findings different between comorbid and non-comorbid patients? The high resolution computed tomography features of the 108 follow-up patients
The aim was to compare the computed tomography (CT) semi-quantitative severity scoring (CT-SS) system assessments of COVID-19 pneumonia on initial and follow-up examinations according to the presence of comorbidities. Of the 278 real-time reverse transcription-polymerase chain reaction positive p...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2024-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/474004 |
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| Summary: | The aim was to compare the computed tomography (CT) semi-quantitative
severity scoring (CT-SS) system assessments of COVID-19 pneumonia on initial and follow-up
examinations according to the presence of comorbidities. Of the 278 real-time reverse
transcription-polymerase chain reaction positive patients, 108 with a follow-up CT scan were
evaluated. Then, all CT images were independently reviewed for CT-SS analysis by two reviewers.
Reviewers were unaware of the patient laboratory and clinical findings. A quarter of patients had
negative findings on their initial CTs. Sixty-one (56.4%) patients showed progression. Disease
progression was more frequently observed in patients with type 2 diabetes mellitus (DM) and
malignancies (p=0.044 and p=0.019, respectively). Follow-up CTs of patients with comorbidities,
especially those with cardiovascular disease (56.4%) and type 2 DM (70.0%), demonstrated
an increased frequency of diff use involvement. Th e white lung sign was more frequently observed
in patients with malignancies (60.0%). In this study, COVID-19 patients with comorbidity
showed a higher rate of disease progression than those without comorbidity. Patients with
comorbidities more frequently had severe CT findings with high CT-SS. These findings may
serve as a guide in the COVID-19 pneumonia follow-up and treatment. |
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| ISSN: | 0353-9466 1333-9451 |