A Higher-Than-Standard-Intensity International Normalized Ratio Goal for Patients Undergoing Mechanical Aortic Valve Replacement With Additional Thrombotic Risk Factors: Protocol for a Systematic Review and Meta-Analysis

A Higher-Than-Standard-Intensity International Normalized Ratio Goal for Patients Undergoing Mechanical Aortic Valve Replacement With Additional Thrombotic Risk Factors: Protocol for a Systematic Review and Meta-Analysis

BackgroundLifelong anticoagulation therapy with vitamin K antagonists is recommended following mechanical aortic valve replacement (MAVR) to prevent valve thrombosis. Current guidelines recommend a standard international normalized ratio (INR) of 2.5 for patients with MAVR wi...

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Main Authors: Myung-Rho Kim, Taha Shaikh, Shawn Wang, Spencer Taylor, Vidhani Goel, Banveet Kaur Khetarpal, Chowdhury Ahsan, Kavita Batra
Format: Article
Language:English
Published: JMIR Publications 2025-07-01
Series:JMIR Research Protocols
Online Access:https://www.researchprotocols.org/2025/1/e73389
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