The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia

The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia

BackgroundDual induction with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has made acute promyelocytic leukemia (APL) a curable disease. However, differentiation syndrome (DS) can be a life-threatening complication of induction therapy. It is considered to result from a severe systemic...

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Bibliographic Details
Main Authors:	Kai Shen, Chenlu Yang, Jie Huang, Xiao Shuai, Ting Niu, Hongbing Ma
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Pharmacology
Subjects:	acute promyelocytic leukemia acute kidney injury renal failure all-trans retinoic acid arsenic trioxide differentiation syndrome
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1540409/full
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