Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter?
Newborn infants with maternal-fetal ABO incompatibility are at a greater risk for developing subsequent significant hyperbilirubinemia, and therefore, prediction of probable risk factors, such as the degree of hemolysis, gains importance. In this study, we aimed to evaluate the effect of feta...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2013-10-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/1542 |
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| author | Sinem Akgül Ayşe Korkmaz Sule Yiğit Murat Yurdakök |
| author_facet | Sinem Akgül Ayşe Korkmaz Sule Yiğit Murat Yurdakök |
| author_sort | Sinem Akgül |
| collection | DOAJ |
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Newborn infants with maternal-fetal ABO incompatibility are at a greater risk for developing subsequent significant hyperbilirubinemia, and therefore, prediction of probable risk factors, such as the degree of hemolysis, gains importance. In this study, we aimed to evaluate the effect of fetal-neonatal blood group on the severity of hemolysis and jaundice due to maternal-fetal ABO incompatibility. In a retrospective analysis of 166 cases with ABO hemolytic disease of the newborn, risk factors for the severity of jaundice were compared in infants with blood group A or B. Both groups had similar demographic parameters such as birth weight, gender and day of admission. Similarly, there were no statistically significant differences in hematological parameters, such as initial hemoglobin levels, initial and final indirect bilirubin levels, frequency of positive direct Coombs test and hemolytic findings on peripheral blood smear, duration of phototherapy, number of exchange transfusions, and intravenous immunoglobulin (IVIG) therapy (p>0.05). We conclude that blood type has no effect on the severity of the hemolytic jaundice in ABO incompatibility.
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| format | Article |
| id | doaj-art-84846a4a8fbe4c978e2e8a56e80bdea5 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2013-10-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-84846a4a8fbe4c978e2e8a56e80bdea52025-08-20T02:01:56ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212013-10-01555Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter?Sinem Akgül0Ayşe KorkmazSule YiğitMurat YurdakökDepartment of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. sinemhusnu@yahoo.com. Newborn infants with maternal-fetal ABO incompatibility are at a greater risk for developing subsequent significant hyperbilirubinemia, and therefore, prediction of probable risk factors, such as the degree of hemolysis, gains importance. In this study, we aimed to evaluate the effect of fetal-neonatal blood group on the severity of hemolysis and jaundice due to maternal-fetal ABO incompatibility. In a retrospective analysis of 166 cases with ABO hemolytic disease of the newborn, risk factors for the severity of jaundice were compared in infants with blood group A or B. Both groups had similar demographic parameters such as birth weight, gender and day of admission. Similarly, there were no statistically significant differences in hematological parameters, such as initial hemoglobin levels, initial and final indirect bilirubin levels, frequency of positive direct Coombs test and hemolytic findings on peripheral blood smear, duration of phototherapy, number of exchange transfusions, and intravenous immunoglobulin (IVIG) therapy (p>0.05). We conclude that blood type has no effect on the severity of the hemolytic jaundice in ABO incompatibility. https://turkjpediatr.org/article/view/1542 |
| spellingShingle | Sinem Akgül Ayşe Korkmaz Sule Yiğit Murat Yurdakök Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? The Turkish Journal of Pediatrics |
| title | Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? |
| title_full | Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? |
| title_fullStr | Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? |
| title_full_unstemmed | Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? |
| title_short | Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? |
| title_sort | neonatal hyperbilirubinemia due to abo incompatibility does blood group matter |
| url | https://turkjpediatr.org/article/view/1542 |
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