Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations
Osteoarthritis (OA) is the most wide-spread and socially significant disease of musculoskeletal system. Systemic inflammation and formation of proinflammatory cytokines underlie OA, which, in its turn, conditions keeping pain syndrome and cartilage degradation. Currently, theory of chondropenia, due...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/650 |
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| author | A. V. Naumov N. O. Hovasova O. N. Tkacheva |
| author_facet | A. V. Naumov N. O. Hovasova O. N. Tkacheva |
| author_sort | A. V. Naumov |
| collection | DOAJ |
| description | Osteoarthritis (OA) is the most wide-spread and socially significant disease of musculoskeletal system. Systemic inflammation and formation of proinflammatory cytokines underlie OA, which, in its turn, conditions keeping pain syndrome and cartilage degradation. Currently, theory of chondropenia, due to age-related reduction of glycosaminoglycans, is actively developed. Modern complex OA therapy should include glycosaminoglycans. |
| format | Article |
| id | doaj-art-8480c1e5a7e84767be2de48fc507cbfd |
| institution | DOAJ |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-8480c1e5a7e84767be2de48fc507cbfd2025-08-20T03:20:17ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-01012649Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestationsA. V. Naumov0N. O. Hovasova1O. N. Tkacheva2ФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФOsteoarthritis (OA) is the most wide-spread and socially significant disease of musculoskeletal system. Systemic inflammation and formation of proinflammatory cytokines underlie OA, which, in its turn, conditions keeping pain syndrome and cartilage degradation. Currently, theory of chondropenia, due to age-related reduction of glycosaminoglycans, is actively developed. Modern complex OA therapy should include glycosaminoglycans.https://journal.lvrach.ru/jour/article/view/650osteoarthritischronic painproinflammatory cytokineschondropeniaglycosaminoglycans |
| spellingShingle | A. V. Naumov N. O. Hovasova O. N. Tkacheva Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations Лечащий Врач osteoarthritis chronic pain proinflammatory cytokines chondropenia glycosaminoglycans |
| title | Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations |
| title_full | Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations |
| title_fullStr | Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations |
| title_full_unstemmed | Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations |
| title_short | Chondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestations |
| title_sort | chondropenia followed by epidemic of osteoarthritis from joint aging to the clinical manifestations |
| topic | osteoarthritis chronic pain proinflammatory cytokines chondropenia glycosaminoglycans |
| url | https://journal.lvrach.ru/jour/article/view/650 |
| work_keys_str_mv | AT avnaumov chondropeniafollowedbyepidemicofosteoarthritisfromjointagingtotheclinicalmanifestations AT nohovasova chondropeniafollowedbyepidemicofosteoarthritisfromjointagingtotheclinicalmanifestations AT ontkacheva chondropeniafollowedbyepidemicofosteoarthritisfromjointagingtotheclinicalmanifestations |