Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents

Abstract Background Adolescents exhibit a high prevalence of mental health disorders, with more than half of all cases emerging before the age of 14 years. Since the advent of the COVID-19 pandemic, there has been a marked upsurge in anxiety and depression among adolescents across several nations. E...

Full description

Saved in:
Bibliographic Details
Main Authors: Yanli Zhao, Jiahua Xu, Jie Zhang, Jiaqi Song, Ning Yang, Hongzhen Fan, Zhe Dong, Shuping Tan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-024-04650-8
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850129410714238976
author Yanli Zhao
Jiahua Xu
Jie Zhang
Jiaqi Song
Ning Yang
Hongzhen Fan
Zhe Dong
Shuping Tan
author_facet Yanli Zhao
Jiahua Xu
Jie Zhang
Jiaqi Song
Ning Yang
Hongzhen Fan
Zhe Dong
Shuping Tan
author_sort Yanli Zhao
collection DOAJ
description Abstract Background Adolescents exhibit a high prevalence of mental health disorders, with more than half of all cases emerging before the age of 14 years. Since the advent of the COVID-19 pandemic, there has been a marked upsurge in anxiety and depression among adolescents across several nations. Emotional disorders often lead to severe outcomes, including school absenteeism, self-harm, and suicidal tendencies. The suboptimal efficacy of pharmacotherapy, compounded by limited availability and substantial costs associated with individual psychotherapy, underscores the critical need for identifying simple yet efficacious psychotherapeutic interventions suitable for both individual and group settings. Tension and Trauma Release Exercise (TRE) is a mind-body therapeutic approach that efficiently alleviates symptoms of anxiety and depression. This randomized controlled trial (RCT) aims to evaluate the effectiveness of a mother-child intervention model using TRE in enhancing the clinical management of adolescent patients diagnosed with emotional disorders. Methods This study recruits 140 dyads of adolescents with emotional disorders and their mothers, randomly assigned to intervention or control groups. The intervention arm combines eight weeks of standard pharmacotherapy with an eight-week TRE group therapy, assessing at baseline, post-8-week treatment, and three-month follow-up. Initially, controls receive eight weeks of standard medication with parallel assessments, later transitioning to the same TRE intervention while maintaining continuous evaluation. The study further examines the influence of maternal emotional health on adolescent treatment response and investigates associated neurophysiological and psychological mechanisms. Discussion This research endeavors to identify a straightforward and potent body-oriented psychological intervention that could improve the clinical outcomes for adolescent patients with emotional disorders. Such findings would carry profound implications not only for the healthy development of teenagers but also for potentially mitigating the burden on families, educational institutions, and society as a whole. Trial registration ChiCTR2100044553, Registered March 24, 2021.
format Article
id doaj-art-8474d56fcb914020b1e5eb108ca35fad
institution OA Journals
issn 2662-7671
language English
publishDate 2024-11-01
publisher BMC
record_format Article
series BMC Complementary Medicine and Therapies
spelling doaj-art-8474d56fcb914020b1e5eb108ca35fad2025-08-20T02:33:00ZengBMCBMC Complementary Medicine and Therapies2662-76712024-11-0124111510.1186/s12906-024-04650-8Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescentsYanli Zhao0Jiahua Xu1Jie Zhang2Jiaqi Song3Ning Yang4Hongzhen Fan5Zhe Dong6Shuping Tan7Psychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolState Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal UniversityPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolPsychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical SchoolAbstract Background Adolescents exhibit a high prevalence of mental health disorders, with more than half of all cases emerging before the age of 14 years. Since the advent of the COVID-19 pandemic, there has been a marked upsurge in anxiety and depression among adolescents across several nations. Emotional disorders often lead to severe outcomes, including school absenteeism, self-harm, and suicidal tendencies. The suboptimal efficacy of pharmacotherapy, compounded by limited availability and substantial costs associated with individual psychotherapy, underscores the critical need for identifying simple yet efficacious psychotherapeutic interventions suitable for both individual and group settings. Tension and Trauma Release Exercise (TRE) is a mind-body therapeutic approach that efficiently alleviates symptoms of anxiety and depression. This randomized controlled trial (RCT) aims to evaluate the effectiveness of a mother-child intervention model using TRE in enhancing the clinical management of adolescent patients diagnosed with emotional disorders. Methods This study recruits 140 dyads of adolescents with emotional disorders and their mothers, randomly assigned to intervention or control groups. The intervention arm combines eight weeks of standard pharmacotherapy with an eight-week TRE group therapy, assessing at baseline, post-8-week treatment, and three-month follow-up. Initially, controls receive eight weeks of standard medication with parallel assessments, later transitioning to the same TRE intervention while maintaining continuous evaluation. The study further examines the influence of maternal emotional health on adolescent treatment response and investigates associated neurophysiological and psychological mechanisms. Discussion This research endeavors to identify a straightforward and potent body-oriented psychological intervention that could improve the clinical outcomes for adolescent patients with emotional disorders. Such findings would carry profound implications not only for the healthy development of teenagers but also for potentially mitigating the burden on families, educational institutions, and society as a whole. Trial registration ChiCTR2100044553, Registered March 24, 2021.https://doi.org/10.1186/s12906-024-04650-8Neurogenic tremorAdolescentsEmotional disordersAnxietyTension and Trauma Release Exercise (TRE)Randomized controlled trial (RCT)
spellingShingle Yanli Zhao
Jiahua Xu
Jie Zhang
Jiaqi Song
Ning Yang
Hongzhen Fan
Zhe Dong
Shuping Tan
Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
BMC Complementary Medicine and Therapies
Neurogenic tremor
Adolescents
Emotional disorders
Anxiety
Tension and Trauma Release Exercise (TRE)
Randomized controlled trial (RCT)
title Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
title_full Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
title_fullStr Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
title_full_unstemmed Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
title_short Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
title_sort study protocol for a randomized controlled trial evaluating the effectiveness of a mother child intervention model of neurogenic tremor as an add on to treatment for emotional disorders in adolescents
topic Neurogenic tremor
Adolescents
Emotional disorders
Anxiety
Tension and Trauma Release Exercise (TRE)
Randomized controlled trial (RCT)
url https://doi.org/10.1186/s12906-024-04650-8
work_keys_str_mv AT yanlizhao studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT jiahuaxu studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT jiezhang studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT jiaqisong studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT ningyang studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT hongzhenfan studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT zhedong studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents
AT shupingtan studyprotocolforarandomizedcontrolledtrialevaluatingtheeffectivenessofamotherchildinterventionmodelofneurogenictremorasanaddontotreatmentforemotionaldisordersinadolescents