Congenital sialidosis

Congenital sialidosis is a rare disease resulting from the absence of neurominidase and presenting with hydrops fetalis, hepatosplenomegaly, dysmorphic features, vacuolated lymphocytes and extensive vacuolation of the connective tissue. Elevated levels of sialooligosaccharides in the urine is...

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Bibliographic Details
Main Authors: F Ovali, N Samanci, A Güray, Z Akdoğan, C Akdeniz, T Dağoğlu, I Petorak
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 1998-07-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/3334
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Summary:Congenital sialidosis is a rare disease resulting from the absence of neurominidase and presenting with hydrops fetalis, hepatosplenomegaly, dysmorphic features, vacuolated lymphocytes and extensive vacuolation of the connective tissue. Elevated levels of sialooligosaccharides in the urine is characteristic. We describe a newborn baby with congenital sialidosis and discuss the difficulties in reaching the diagnosis.
ISSN:0041-4301
2791-6421