Clinical features and treatment results in children with hemangioma
Hemangioma is a frequent disease which has a proliferative and involution phase. In this single center retrospective study, we evaluated clinical and therapeutic features of hemangiomas in children (n: 49). The median (range) age at onset and at admission were 21 days (10 days-156 months) and 7 mon...
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Hacettepe University Institute of Child Health
2017-06-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/983 |
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| author | Erman Ataş Ozan Koç Hatice A Artık |
| author_facet | Erman Ataş Ozan Koç Hatice A Artık |
| author_sort | Erman Ataş |
| collection | DOAJ |
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Hemangioma is a frequent disease which has a proliferative and involution phase. In this single center retrospective study, we evaluated clinical and therapeutic features of hemangiomas in children (n: 49). The median (range) age at onset and at admission were 21 days (10 days-156 months) and 7 months (0.25-192 months), respectively. The localization of lesions was: head region (n: 28; 57.2%), trunk (n: 8; 16.3%) trunk, limb (n: 8; 16.3%), and neck region (n: 5; 10.2%) neck region. Seventeen patients (34.7%) were treated. Following treatments were used: propranolol alone in 12 (24.5%) patients, steroid alone in 2 (4.1%) patients, prednisone plus propranolol in 2 (4.1%) patients, and propranolol plus surgery in 1 (2.0%) patient. The number of hemangioma (n > 1) (p = 0.026, OR = 9.5, 95% CI 1.3-69.2) and treatment other than observation (p = 0.008, OR = 10.5, 95% CI 1.8-59.1) were significant predictors in the univariate analysis; treatment other than observation was an independent predictor for clinical response (p = 0.014, OR = 9.8, 95% CI 1.5-90.9).
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| format | Article |
| id | doaj-art-845552c49ff54384bcfb92bb457fb45d |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2017-06-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-845552c49ff54384bcfb92bb457fb45d2025-08-20T03:16:22ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212017-06-0159310.24953/turkjped.2017.03.004Clinical features and treatment results in children with hemangiomaErman Ataş0Ozan Koç1Hatice A Artık2Department of Pediatric Oncology, Universitiy of Health Sciences, Gülhane Training and Research Hospital, Pediatrics, Ankara, Turkey.Department of Pediatrics, Universitiy of Health Sciences, Gülhane Training and Research Hospital, Pediatrics, Ankara, Turkey.Department of Dermatology, University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Desearch Hospital, Ankara, Turkey. Hemangioma is a frequent disease which has a proliferative and involution phase. In this single center retrospective study, we evaluated clinical and therapeutic features of hemangiomas in children (n: 49). The median (range) age at onset and at admission were 21 days (10 days-156 months) and 7 months (0.25-192 months), respectively. The localization of lesions was: head region (n: 28; 57.2%), trunk (n: 8; 16.3%) trunk, limb (n: 8; 16.3%), and neck region (n: 5; 10.2%) neck region. Seventeen patients (34.7%) were treated. Following treatments were used: propranolol alone in 12 (24.5%) patients, steroid alone in 2 (4.1%) patients, prednisone plus propranolol in 2 (4.1%) patients, and propranolol plus surgery in 1 (2.0%) patient. The number of hemangioma (n > 1) (p = 0.026, OR = 9.5, 95% CI 1.3-69.2) and treatment other than observation (p = 0.008, OR = 10.5, 95% CI 1.8-59.1) were significant predictors in the univariate analysis; treatment other than observation was an independent predictor for clinical response (p = 0.014, OR = 9.8, 95% CI 1.5-90.9). https://turkjpediatr.org/article/view/983childrenclinical featureshemangiomaoutcometreatment |
| spellingShingle | Erman Ataş Ozan Koç Hatice A Artık Clinical features and treatment results in children with hemangioma The Turkish Journal of Pediatrics children clinical features hemangioma outcome treatment |
| title | Clinical features and treatment results in children with hemangioma |
| title_full | Clinical features and treatment results in children with hemangioma |
| title_fullStr | Clinical features and treatment results in children with hemangioma |
| title_full_unstemmed | Clinical features and treatment results in children with hemangioma |
| title_short | Clinical features and treatment results in children with hemangioma |
| title_sort | clinical features and treatment results in children with hemangioma |
| topic | children clinical features hemangioma outcome treatment |
| url | https://turkjpediatr.org/article/view/983 |
| work_keys_str_mv | AT ermanatas clinicalfeaturesandtreatmentresultsinchildrenwithhemangioma AT ozankoc clinicalfeaturesandtreatmentresultsinchildrenwithhemangioma AT haticeaartık clinicalfeaturesandtreatmentresultsinchildrenwithhemangioma |