Severity-specific immune landscape of COVID-19 revealed by single-cell sequencing

Severity-specific immune landscape of COVID-19 revealed by single-cell sequencing

Abstract The Coronavirus disease 2019 (COVID-19) has rapidly become the worst pandemic since the 1918 influenza pandemic. Studies have shown that severe COVID-19 patients have immune dysfunction. To characterize the dysregulated immune response to SARS-CoV-2 infection, we performed a comprehensive a...

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Bibliographic Details
Main Authors: Hongying Zhao, Meiting Fei, Wentong Yu, Zhichao Geng, Jing Bai, Li Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
COVID-19
Disease progression stage specific
Immune landscape
ScRNA-seq
ScV(D)J-seq
Online Access:https://doi.org/10.1038/s41598-025-13888-2
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