Genetic and molecular basis of abnormal BOLD signaling variability in patients with major depressive disorder after electroconvulsive therapy

Genetic and molecular basis of abnormal BOLD signaling variability in patients with major depressive disorder after electroconvulsive therapy

Abstract Electroconvulsive therapy (ECT) is an effective and rapid neuromodulatory intervention for treatment-resistant major depressive disorders (MDD). However, the precise mechanisms underlying their efficacies remain unclear. Resting-state functional magnetic resonance imaging (fMRI) data were c...

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Bibliographic Details
Main Authors: Siyu Fan, Yulin Zhang, Rui Qian, Jie Hu, Hao Zheng, Wentao Dai, Yang Ji, Yue Wu, Xiaohui Xie, Si Xu, Gong-Jun Ji, Yanghua Tian, Kai Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03330-6
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