Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more

Introduction. In case of donor heart shortage and expanding pool of patients waiting for heart transplantation (OHTx) liberalization of donor selection, especially use of donors with left ventricular hypertrophy (LVH), may be one of most realistic methods to extending number of OHTx.Aim: to evaluate...

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Main Authors: V. N. Poptsov, E. A. Spirina, S. Yu. Ustin, S. A. Masutin, A. A. Dogonacheva, V. Yu. Voronkov, E. N. Zolotova, A. I. Skokova
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Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2019-05-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/984
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author V. N. Poptsov
E. A. Spirina
S. Yu. Ustin
S. A. Masutin
A. A. Dogonacheva
V. Yu. Voronkov
E. N. Zolotova
A. I. Skokova
author_facet V. N. Poptsov
E. A. Spirina
S. Yu. Ustin
S. A. Masutin
A. A. Dogonacheva
V. Yu. Voronkov
E. N. Zolotova
A. I. Skokova
author_sort V. N. Poptsov
collection DOAJ
description Introduction. In case of donor heart shortage and expanding pool of patients waiting for heart transplantation (OHTx) liberalization of donor selection, especially use of donors with left ventricular hypertrophy (LVH), may be one of most realistic methods to extending number of OHTx.Aim: to evaluate early and late outcomes after OHTx from donors with LVH ≥1.5 cm.Methods. We reviewed 160 heart recipients who underwent OHTx from donors with LVH 1.5 cm or more from 2011 to 2017.Results. The duration of anesthesia was 6.5 ± 0.7 h, surgery – 4.7 ± 0.3 h, cardiopulmonary bypass – 63–290 (145 ± 47) min and ischemia time was – 86–426 (168 ± 44) min. ICU stay was 7.4 ± 8.5 days. Hospital mortality in the study group was 8,1% (n = 13) and 30-day survival was 91.9%. Patients with or without donor LVH had similar early and long-term survival (p = 0.659).Conclusions. Own experience demonstrates the satisfactory results of HT from donors with LVH. In more cases, LV systolic function of cardiac allograft quickly normalized in the early period after HT.
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spelling doaj-art-843941a7967848e88802184a73a3fa5a2025-08-20T03:21:06ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912019-05-0121171610.15825/1995-1191-2019-1-7-16754Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and moreV. N. Poptsov0E. A. Spirina1S. Yu. Ustin2S. A. Masutin3A. A. Dogonacheva4V. Yu. Voronkov5E. N. Zolotova6A. I. Skokova7V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationIntroduction. In case of donor heart shortage and expanding pool of patients waiting for heart transplantation (OHTx) liberalization of donor selection, especially use of donors with left ventricular hypertrophy (LVH), may be one of most realistic methods to extending number of OHTx.Aim: to evaluate early and late outcomes after OHTx from donors with LVH ≥1.5 cm.Methods. We reviewed 160 heart recipients who underwent OHTx from donors with LVH 1.5 cm or more from 2011 to 2017.Results. The duration of anesthesia was 6.5 ± 0.7 h, surgery – 4.7 ± 0.3 h, cardiopulmonary bypass – 63–290 (145 ± 47) min and ischemia time was – 86–426 (168 ± 44) min. ICU stay was 7.4 ± 8.5 days. Hospital mortality in the study group was 8,1% (n = 13) and 30-day survival was 91.9%. Patients with or without donor LVH had similar early and long-term survival (p = 0.659).Conclusions. Own experience demonstrates the satisfactory results of HT from donors with LVH. In more cases, LV systolic function of cardiac allograft quickly normalized in the early period after HT.https://journal.transpl.ru/vtio/article/view/984heart transplantationleft ventricular hypertrophy
spellingShingle V. N. Poptsov
E. A. Spirina
S. Yu. Ustin
S. A. Masutin
A. A. Dogonacheva
V. Yu. Voronkov
E. N. Zolotova
A. I. Skokova
Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
Вестник трансплантологии и искусственных органов
heart transplantation
left ventricular hypertrophy
title Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
title_full Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
title_fullStr Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
title_full_unstemmed Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
title_short Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more
title_sort transplantation of cardiac allografts with left ventricular hypertrophy 1 5 cm and more
topic heart transplantation
left ventricular hypertrophy
url https://journal.transpl.ru/vtio/article/view/984
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AT aadogonacheva transplantationofcardiacallograftswithleftventricularhypertrophy15cmandmore
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