Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy

Osteoarthritis (OA) is a widespread disease accompanied by persistent joint damage with obvious functional failure, which leads to early disability in patients. In OA, different groups of joints are involved in the pathological process. Hand joints are one of the classical sites of OA. The paper dis...

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Main Authors: N. A. Shostak, N. G. Pravdyuk, A. M. Lila, O. A. Gromova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2019-10-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/971
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author N. A. Shostak
N. G. Pravdyuk
A. M. Lila
O. A. Gromova
author_facet N. A. Shostak
N. G. Pravdyuk
A. M. Lila
O. A. Gromova
author_sort N. A. Shostak
collection DOAJ
description Osteoarthritis (OA) is a widespread disease accompanied by persistent joint damage with obvious functional failure, which leads to early disability in patients. In OA, different groups of joints are involved in the pathological process. Hand joints are one of the classical sites of OA. The paper discusses the role of mechanical load, genetic factors, and sex hormone deficiency in the development of the disease. The treatment policy includes a set of non-pharmacological, pharmacological, and surgical methods.
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series Современная ревматология
spelling doaj-art-8436a8acb7e64c07a03e753fe4de71c32025-08-20T03:20:59ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2019-10-0113413013610.14412/1996-7012-2019-4-130-1362223Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapyN. A. Shostak0N. G. Pravdyuk1A. M. Lila2O. A. Gromova3N.I. Pirogov Russian National Research Medical University, Ministry of Heath of RussiaN.I. Pirogov Russian National Research Medical University, Ministry of Heath of RussiaV.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaInstitute of Pharmacoinformatics, Federal Research Center «Informatics and Management», Russian Academy of SciencesOsteoarthritis (OA) is a widespread disease accompanied by persistent joint damage with obvious functional failure, which leads to early disability in patients. In OA, different groups of joints are involved in the pathological process. Hand joints are one of the classical sites of OA. The paper discusses the role of mechanical load, genetic factors, and sex hormone deficiency in the development of the disease. The treatment policy includes a set of non-pharmacological, pharmacological, and surgical methods.https://mrj.ima-press.net/mrj/article/view/971hand osteoarthritisnonsteroidal anti-inflammatory drugscapsaicinchondroitin sulfateglucosamine sulfatechondroguardsustaguard arthrovitamin destrogen-containing drugstargeted therapy
spellingShingle N. A. Shostak
N. G. Pravdyuk
A. M. Lila
O. A. Gromova
Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
Современная ревматология
hand osteoarthritis
nonsteroidal anti-inflammatory drugs
capsaicin
chondroitin sulfate
glucosamine sulfate
chondroguard
sustaguard arthro
vitamin d
estrogen-containing drugs
targeted therapy
title Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
title_full Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
title_fullStr Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
title_full_unstemmed Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
title_short Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
title_sort hand osteoarthritis pathogenesis diagnosis and approaches to therapy
topic hand osteoarthritis
nonsteroidal anti-inflammatory drugs
capsaicin
chondroitin sulfate
glucosamine sulfate
chondroguard
sustaguard arthro
vitamin d
estrogen-containing drugs
targeted therapy
url https://mrj.ima-press.net/mrj/article/view/971
work_keys_str_mv AT nashostak handosteoarthritispathogenesisdiagnosisandapproachestotherapy
AT ngpravdyuk handosteoarthritispathogenesisdiagnosisandapproachestotherapy
AT amlila handosteoarthritispathogenesisdiagnosisandapproachestotherapy
AT oagromova handosteoarthritispathogenesisdiagnosisandapproachestotherapy