Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum

ABSTRACT Erythema nodosum (EN) can be an atypical manifestation of rheumatoid arthritis (RA), as seen in this case of a 35‐year‐old woman initially misdiagnosed with cellulitis. Despite negative cultures and antibiotic treatment, further evaluation revealed elevated rheumatoid factor and anti‐CCP an...

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Main Authors: Laxman Wagle, Parmartha Basnyat, Anuj Timshina, Rashmita Regmi
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.70566
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author Laxman Wagle
Parmartha Basnyat
Anuj Timshina
Rashmita Regmi
author_facet Laxman Wagle
Parmartha Basnyat
Anuj Timshina
Rashmita Regmi
author_sort Laxman Wagle
collection DOAJ
description ABSTRACT Erythema nodosum (EN) can be an atypical manifestation of rheumatoid arthritis (RA), as seen in this case of a 35‐year‐old woman initially misdiagnosed with cellulitis. Despite negative cultures and antibiotic treatment, further evaluation revealed elevated rheumatoid factor and anti‐CCP antibodies, confirming RA. Steroids led to symptom resolution.
format Article
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language English
publishDate 2025-06-01
publisher Wiley
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series Clinical Case Reports
spelling doaj-art-843597f3f772462f8ece27df4ad11a862025-08-20T02:10:28ZengWileyClinical Case Reports2050-09042025-06-01136n/an/a10.1002/ccr3.70566Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema NodosumLaxman Wagle0Parmartha Basnyat1Anuj Timshina2Rashmita Regmi3Department of Internal Medicine Ascension Saint Agnes Hospital Baltimore Maryland USADepartment of Internal Medicine Ascension Saint Agnes Hospital Baltimore Maryland USADepartment of Internal Medicine Patan Academy of Health Science Kathmandu NepalDepartment of Nursing Karnali Academy of Health Science Jumla NepalABSTRACT Erythema nodosum (EN) can be an atypical manifestation of rheumatoid arthritis (RA), as seen in this case of a 35‐year‐old woman initially misdiagnosed with cellulitis. Despite negative cultures and antibiotic treatment, further evaluation revealed elevated rheumatoid factor and anti‐CCP antibodies, confirming RA. Steroids led to symptom resolution.https://doi.org/10.1002/ccr3.70566anti‐cyclic citrullinated peptide antibodyerythema nodosumMiescher's granulomarheumatoid arthritissteroid therapy
spellingShingle Laxman Wagle
Parmartha Basnyat
Anuj Timshina
Rashmita Regmi
Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
Clinical Case Reports
anti‐cyclic citrullinated peptide antibody
erythema nodosum
Miescher's granuloma
rheumatoid arthritis
steroid therapy
title Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
title_full Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
title_fullStr Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
title_full_unstemmed Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
title_short Atypical Presentation of Rheumatoid Arthritis With Erythema Nodosum Mimicking Cellulitis: A Case Report and Literature Review of Erythema Nodosum
title_sort atypical presentation of rheumatoid arthritis with erythema nodosum mimicking cellulitis a case report and literature review of erythema nodosum
topic anti‐cyclic citrullinated peptide antibody
erythema nodosum
Miescher's granuloma
rheumatoid arthritis
steroid therapy
url https://doi.org/10.1002/ccr3.70566
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