Sex Steroids and Bone Health Status in Men
Male osteoporosis is a health problem which deserves more attention as nearly 30% of osteoporotic fractures happen in men aged 50 years and above. Although men do not experience an accelerated bone loss phase and testosterone deficiency is not a universal characteristic for aged men, osteoporosis du...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/208719 |
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| _version_ | 1849402087500152832 |
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| author | Kok-Yong Chin Soelaiman Ima-Nirwana |
| author_facet | Kok-Yong Chin Soelaiman Ima-Nirwana |
| author_sort | Kok-Yong Chin |
| collection | DOAJ |
| description | Male osteoporosis is a health problem which deserves more attention as nearly 30% of osteoporotic fractures happen in men aged 50 years and above. Although men do not experience an accelerated bone loss phase and testosterone deficiency is not a universal characteristic for aged men, osteoporosis due to age-related testosterone deficiency does have a negative impact on bone health status of men. Observations from epidemiological studies indicate that elderly men with higher testosterone can preserve their BMD better and thus are less prone to fracture. Observations on men with estrogen resistance or aromatase deficiency indicate that estrogen is equally important in the maintenance of bone health status. This had been validated in several epidemiological studies which found that the relationships between estrogen and bone health indices are significant and sometimes stronger than testosterone. Studies on the relationship between quantitative ultrasound and bone remodeling markers suggest that testosterone and estrogen may have differential effects on bone, but further evidence was needed. In conclusion, both testosterone and estrogen are important in the maintenance of bone health in men. |
| format | Article |
| id | doaj-art-84354b87627443c29602dceda3dc6edd |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-84354b87627443c29602dceda3dc6edd2025-08-20T03:37:38ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/208719208719Sex Steroids and Bone Health Status in MenKok-Yong Chin0Soelaiman Ima-Nirwana1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, MalaysiaDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, MalaysiaMale osteoporosis is a health problem which deserves more attention as nearly 30% of osteoporotic fractures happen in men aged 50 years and above. Although men do not experience an accelerated bone loss phase and testosterone deficiency is not a universal characteristic for aged men, osteoporosis due to age-related testosterone deficiency does have a negative impact on bone health status of men. Observations from epidemiological studies indicate that elderly men with higher testosterone can preserve their BMD better and thus are less prone to fracture. Observations on men with estrogen resistance or aromatase deficiency indicate that estrogen is equally important in the maintenance of bone health status. This had been validated in several epidemiological studies which found that the relationships between estrogen and bone health indices are significant and sometimes stronger than testosterone. Studies on the relationship between quantitative ultrasound and bone remodeling markers suggest that testosterone and estrogen may have differential effects on bone, but further evidence was needed. In conclusion, both testosterone and estrogen are important in the maintenance of bone health in men.http://dx.doi.org/10.1155/2012/208719 |
| spellingShingle | Kok-Yong Chin Soelaiman Ima-Nirwana Sex Steroids and Bone Health Status in Men International Journal of Endocrinology |
| title | Sex Steroids and Bone Health Status in Men |
| title_full | Sex Steroids and Bone Health Status in Men |
| title_fullStr | Sex Steroids and Bone Health Status in Men |
| title_full_unstemmed | Sex Steroids and Bone Health Status in Men |
| title_short | Sex Steroids and Bone Health Status in Men |
| title_sort | sex steroids and bone health status in men |
| url | http://dx.doi.org/10.1155/2012/208719 |
| work_keys_str_mv | AT kokyongchin sexsteroidsandbonehealthstatusinmen AT soelaimanimanirwana sexsteroidsandbonehealthstatusinmen |