Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients

The main aim of the study was to identify predictors of the effects of lifestyle intervention on diabetes mellitus type 2 patients by means of multivariate analysis. Data from a previously published randomised clinical trial, which compared the effects of a rehabilitation programme including standar...

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Main Authors: Ramune Jacobsen, Eva Vadstrup, Michael Røder, Anne Frølich
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/962951
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author Ramune Jacobsen
Eva Vadstrup
Michael Røder
Anne Frølich
author_facet Ramune Jacobsen
Eva Vadstrup
Michael Røder
Anne Frølich
author_sort Ramune Jacobsen
collection DOAJ
description The main aim of the study was to identify predictors of the effects of lifestyle intervention on diabetes mellitus type 2 patients by means of multivariate analysis. Data from a previously published randomised clinical trial, which compared the effects of a rehabilitation programme including standardised education and physical training sessions in the municipality’s health care centre with the same duration of individual counseling in the diabetes outpatient clinic, were used. Data from 143 diabetes patients were analysed. The merged lifestyle intervention resulted in statistically significant improvements in patients’ systolic blood pressure, waist circumference, exercise capacity, glycaemic control, and some aspects of general health-related quality of life. The linear multivariate regression models explained 45% to 80% of the variance in these improvements. The baseline outcomes in accordance to the logic of the regression to the mean phenomenon were the only statistically significant and robust predictors in all regression models. These results are important from a clinical point of view as they highlight the more urgent need for and better outcomes following lifestyle intervention for those patients who have worse general and disease-specific health.
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issn 1537-744X
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spelling doaj-art-843320990fe1464bb5fec3d0156875f12025-08-20T03:37:38ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/962951962951Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 PatientsRamune Jacobsen0Eva Vadstrup1Michael Røder2Anne Frølich3Section for Social Pharmacy, University of Copenhagen, Jagtvej 160, 1st Floor, 2400 Copenhagen, DenmarkDepartment of Oncology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, DenmarkDepartment of Cardiology and Endocrinology, Hillerød University Hospital, Dyrehavevej 29, 3400 Hillerød, DenmarkDepartment of Integrated Healthcare, Bispebjerg University Hospital, Bispebjerg Bakke 11 B, 2400 Copenhagen, DenmarkThe main aim of the study was to identify predictors of the effects of lifestyle intervention on diabetes mellitus type 2 patients by means of multivariate analysis. Data from a previously published randomised clinical trial, which compared the effects of a rehabilitation programme including standardised education and physical training sessions in the municipality’s health care centre with the same duration of individual counseling in the diabetes outpatient clinic, were used. Data from 143 diabetes patients were analysed. The merged lifestyle intervention resulted in statistically significant improvements in patients’ systolic blood pressure, waist circumference, exercise capacity, glycaemic control, and some aspects of general health-related quality of life. The linear multivariate regression models explained 45% to 80% of the variance in these improvements. The baseline outcomes in accordance to the logic of the regression to the mean phenomenon were the only statistically significant and robust predictors in all regression models. These results are important from a clinical point of view as they highlight the more urgent need for and better outcomes following lifestyle intervention for those patients who have worse general and disease-specific health.http://dx.doi.org/10.1100/2012/962951
spellingShingle Ramune Jacobsen
Eva Vadstrup
Michael Røder
Anne Frølich
Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
The Scientific World Journal
title Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
title_full Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
title_fullStr Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
title_full_unstemmed Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
title_short Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients
title_sort predictors of effects of lifestyle intervention on diabetes mellitus type 2 patients
url http://dx.doi.org/10.1100/2012/962951
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AT michaelrøder predictorsofeffectsoflifestyleinterventionondiabetesmellitustype2patients
AT annefrølich predictorsofeffectsoflifestyleinterventionondiabetesmellitustype2patients