The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases
Obesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune cells. As consequence, increased circulating le...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2010/802078 |
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| _version_ | 1832552367801761792 |
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| author | Carmela Rita Balistreri Calogero Caruso Giuseppina Candore |
| author_facet | Carmela Rita Balistreri Calogero Caruso Giuseppina Candore |
| author_sort | Carmela Rita Balistreri |
| collection | DOAJ |
| description | Obesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune cells. As consequence, increased circulating levels of proinflammatory cytokines, hormone-like molecules, and other inflammatory markers are induced. This determines a chronic active inflammatory condition, associated with the development of the obesity-related inflammatory diseases. This paper describes the role of adipose tissue and the biological effects of many adipokines in these diseases. |
| format | Article |
| id | doaj-art-84275462b22f4c8ca8edc56b1c2001bd |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-84275462b22f4c8ca8edc56b1c2001bd2025-02-03T05:58:47ZengWileyMediators of Inflammation0962-93511466-18612010-01-01201010.1155/2010/802078802078The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory DiseasesCarmela Rita Balistreri0Calogero Caruso1Giuseppina Candore2Immunosenescence Group, Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Corso Tukory 211, 90134, Palermo, ItalyImmunosenescence Group, Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Corso Tukory 211, 90134, Palermo, ItalyImmunosenescence Group, Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Corso Tukory 211, 90134, Palermo, ItalyObesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune cells. As consequence, increased circulating levels of proinflammatory cytokines, hormone-like molecules, and other inflammatory markers are induced. This determines a chronic active inflammatory condition, associated with the development of the obesity-related inflammatory diseases. This paper describes the role of adipose tissue and the biological effects of many adipokines in these diseases.http://dx.doi.org/10.1155/2010/802078 |
| spellingShingle | Carmela Rita Balistreri Calogero Caruso Giuseppina Candore The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases Mediators of Inflammation |
| title | The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases |
| title_full | The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases |
| title_fullStr | The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases |
| title_full_unstemmed | The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases |
| title_short | The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases |
| title_sort | role of adipose tissue and adipokines in obesity related inflammatory diseases |
| url | http://dx.doi.org/10.1155/2010/802078 |
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