Prmt5 is essential for intestinal stem cell maintenance and homeostasis

Prmt5 is essential for intestinal stem cell maintenance and homeostasis

Abstract Intestinal homeostasis relies on the continuous renewal of intestinal stem cells (ISCs), which could be epigenetically regulated. While protein arginine methyltransferase 5 (Prmt5) is known to play a key role in multiple organs as an epigenetic modifier, its specific function in maintaining...

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Bibliographic Details
Main Authors: Li Yang, Xuewen Li, Chenyi Shi, Bing Zhao
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:Cell Regeneration
Subjects:
Prmt5
Intestinal stem cells
Homeostasis
H3K27ac
Online Access:https://doi.org/10.1186/s13619-024-00216-8
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