Pythium insidiosum-antigen enhances neutrophil-mediated killing of zoospores

Pythium insidiosum-antigen enhances neutrophil-mediated killing of zoospores

Abstract Pythium insidiosum-antigen (PIA) immunotherapy has been used to treat human pythiosis. This study compared PIA-stimulated and unstimulated neutrophils on zoospore viability of P. insidiosum strains. We cultured and collected zoospores of 6 P. insidiosum strains, CBS 777.84, ATCC 58643, ATCC...

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Bibliographic Details
Main Authors: Sadeep Medhasi, Apichaya Sriwarom, Nitipong Permpalung, Pattama Torvorapanit, Rongpong Plongla, Ariya Chindamporn, Navaporn Worasilchai
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Immunotherapy
Pythiosis
PIA
Cell viability
Oomycete
Online Access:https://doi.org/10.1038/s41598-025-88962-w
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