Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy
Introduction. Follicular lymphoma in situ (FLIS) is a recently described entity with few cases recognized worldwide. To our knowledge, this is the first FLIS reported from West Africa. Case Presentation. We present the case of a 48-year-old civil servant with axillary lymphadenopathy discovered on r...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2013/481937 |
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| author | Orah Nnamdi Obumneme Igbokwe Uche Banjo Adekunbiola Akinde Ralph Irurhe Nicholas |
| author_facet | Orah Nnamdi Obumneme Igbokwe Uche Banjo Adekunbiola Akinde Ralph Irurhe Nicholas |
| author_sort | Orah Nnamdi Obumneme |
| collection | DOAJ |
| description | Introduction. Follicular lymphoma in situ (FLIS) is a recently described entity with few cases recognized worldwide. To our knowledge, this is the first FLIS reported from West Africa. Case Presentation. We present the case of a 48-year-old civil servant with axillary lymphadenopathy discovered on routine mammography. On histology, a predominant reactive change with aggregates of melanophages was seen prompting a diagnosis of reactive lymphadenopathy. Immunohistochemistry done in our laboratory showed CD10 and Bcl-6 positive germinal centres with a small population of Bcl-2 positive germinal centre centre cells that were limited to some of the germinal centres. Conclusion. This highlights the use of immunohistochemistry in lymph node pathology—a resource which is very limited in our environment. |
| format | Article |
| id | doaj-art-840d8bc8cb314691a381dbb821c685d3 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-840d8bc8cb314691a381dbb821c685d32025-02-03T01:21:41ZengWileyCase Reports in Pathology2090-67812090-679X2013-01-01201310.1155/2013/481937481937Follicular Lymphoma In Situ Presenting as Dermatopathic LymphadenopathyOrah Nnamdi Obumneme0Igbokwe Uche1Banjo Adekunbiola2Akinde Ralph3Irurhe Nicholas4Department of Anatomic and Molecular Pathology, Lagos University Teaching Hospital, P.M.B. 12003, Lagos State, NigeriaDepartment of Cellular Pathology, Queen’s Hospital, Rom Valley Way, Romford, UKDepartment of Anatomic and Molecular Pathology, Lagos University Teaching Hospital, P.M.B. 12003, Lagos State, NigeriaDepartment of Anatomic and Molecular Pathology, Lagos University Teaching Hospital, P.M.B. 12003, Lagos State, NigeriaDepartment of Radiodiagnosis, Lagos University Teaching Hospital, Lagos State, NigeriaIntroduction. Follicular lymphoma in situ (FLIS) is a recently described entity with few cases recognized worldwide. To our knowledge, this is the first FLIS reported from West Africa. Case Presentation. We present the case of a 48-year-old civil servant with axillary lymphadenopathy discovered on routine mammography. On histology, a predominant reactive change with aggregates of melanophages was seen prompting a diagnosis of reactive lymphadenopathy. Immunohistochemistry done in our laboratory showed CD10 and Bcl-6 positive germinal centres with a small population of Bcl-2 positive germinal centre centre cells that were limited to some of the germinal centres. Conclusion. This highlights the use of immunohistochemistry in lymph node pathology—a resource which is very limited in our environment.http://dx.doi.org/10.1155/2013/481937 |
| spellingShingle | Orah Nnamdi Obumneme Igbokwe Uche Banjo Adekunbiola Akinde Ralph Irurhe Nicholas Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy Case Reports in Pathology |
| title | Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy |
| title_full | Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy |
| title_fullStr | Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy |
| title_full_unstemmed | Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy |
| title_short | Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy |
| title_sort | follicular lymphoma in situ presenting as dermatopathic lymphadenopathy |
| url | http://dx.doi.org/10.1155/2013/481937 |
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