Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality

Thyroid hormones play an important role in regulating different metabolism functions and multiple organs’ performance. Changes in the thyroid hormone axis can lead to profound effects on the stability of vital organs and systems, especially the cardiovascular system. Hypothyroidism is classified acc...

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Main Authors: Alvaro Altamirano Ufion, Beenish Zulfiqar, Abdalla Hassan, Roshanak Habibi, Prajwal Boddu
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2017/7539735
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author Alvaro Altamirano Ufion
Beenish Zulfiqar
Abdalla Hassan
Roshanak Habibi
Prajwal Boddu
author_facet Alvaro Altamirano Ufion
Beenish Zulfiqar
Abdalla Hassan
Roshanak Habibi
Prajwal Boddu
author_sort Alvaro Altamirano Ufion
collection DOAJ
description Thyroid hormones play an important role in regulating different metabolism functions and multiple organs’ performance. Changes in the thyroid hormone axis can lead to profound effects on the stability of vital organs and systems, especially the cardiovascular system. Hypothyroidism is classified according to the clinical presentation as overt and subclinical. There is some evidence supporting the benefits of thyroxine hormone replacement for subclinical hypothyroidism on cardiovascular mortality outcomes. However, the clinical relevance of measuring and treating high thyroid-stimulating hormone (TSH) levels in newly diagnosed heart failure patients with preserved ejection fraction requires further study. In this report, we review the current evidence regarding the prognostic significance of subclinical hypothyroidism in heart failure patients with preserved ejection fraction.
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institution Kabale University
issn 2090-8016
2090-0597
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Cardiology Research and Practice
spelling doaj-art-8404918e294f4a5ea8a01161f72934402025-02-03T06:06:00ZengWileyCardiology Research and Practice2090-80162090-05972017-01-01201710.1155/2017/75397357539735Subclinical Hypothyroidism and Its Association with Increased Cardiovascular MortalityAlvaro Altamirano Ufion0Beenish Zulfiqar1Abdalla Hassan2Roshanak Habibi3Prajwal Boddu4Department of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Francis Hospital, Evanston, IL 60202, USAUniversity of Texas, MD Anderson Cancer Center, Houston, TX 77030, USAThyroid hormones play an important role in regulating different metabolism functions and multiple organs’ performance. Changes in the thyroid hormone axis can lead to profound effects on the stability of vital organs and systems, especially the cardiovascular system. Hypothyroidism is classified according to the clinical presentation as overt and subclinical. There is some evidence supporting the benefits of thyroxine hormone replacement for subclinical hypothyroidism on cardiovascular mortality outcomes. However, the clinical relevance of measuring and treating high thyroid-stimulating hormone (TSH) levels in newly diagnosed heart failure patients with preserved ejection fraction requires further study. In this report, we review the current evidence regarding the prognostic significance of subclinical hypothyroidism in heart failure patients with preserved ejection fraction.http://dx.doi.org/10.1155/2017/7539735
spellingShingle Alvaro Altamirano Ufion
Beenish Zulfiqar
Abdalla Hassan
Roshanak Habibi
Prajwal Boddu
Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
Cardiology Research and Practice
title Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
title_full Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
title_fullStr Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
title_full_unstemmed Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
title_short Subclinical Hypothyroidism and Its Association with Increased Cardiovascular Mortality
title_sort subclinical hypothyroidism and its association with increased cardiovascular mortality
url http://dx.doi.org/10.1155/2017/7539735
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AT abdallahassan subclinicalhypothyroidismanditsassociationwithincreasedcardiovascularmortality
AT roshanakhabibi subclinicalhypothyroidismanditsassociationwithincreasedcardiovascularmortality
AT prajwalboddu subclinicalhypothyroidismanditsassociationwithincreasedcardiovascularmortality