Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial
BACKGROUND: Antibiotic-based regimens are frequently used for the treatment of Helicobacter pylori infection. These regimens fail to eradicate H pylori in 15% to 40% of patients, primarily due to antimicrobial resistance and insufficient patient compliance. Effective prevention and eradication of H...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2011/672093 |
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| _version_ | 1832562821377818624 |
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| author | CM den Hoed AC de Vries PBF Mensink CM Dierikx H Suzuki L Capelle H van Dekken R Ouwendijk EJ Kuipers |
| author_facet | CM den Hoed AC de Vries PBF Mensink CM Dierikx H Suzuki L Capelle H van Dekken R Ouwendijk EJ Kuipers |
| author_sort | CM den Hoed |
| collection | DOAJ |
| description | BACKGROUND: Antibiotic-based regimens are frequently used for the treatment of Helicobacter pylori infection. These regimens fail to eradicate H pylori in 15% to 40% of patients, primarily due to antimicrobial resistance and insufficient patient compliance. Effective prevention and eradication of H pylori by passive immunization with orally administered bovine antibodies has been demonstrated in animal studies, and may serve as an alternative therapy in humans. |
| format | Article |
| id | doaj-art-8402f639e28e4554a6599ef1135d1ecc |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-8402f639e28e4554a6599ef1135d1ecc2025-02-03T01:21:41ZengWileyCanadian Journal of Gastroenterology0835-79002011-01-0125420721310.1155/2011/672093Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical TrialCM den Hoed0AC de Vries1PBF Mensink2CM Dierikx3H Suzuki4L Capelle5H van Dekken6R Ouwendijk7EJ Kuipers8Departments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsDepartments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsDepartments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsDepartments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsDepartment of Internal Medicine, Keio University School of Medicine, Tokyo, JapanDepartments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsDepartment of Pathology, Erasmus University Medical Center, The NetherlandsDepartment of Gastroenterology and Hepatology, Ikazia Hospital, Ziekenhuis, The NetherlandsDepartments of Gastroenterology, Erasmus University Medical Center, Rotterdam, The NetherlandsBACKGROUND: Antibiotic-based regimens are frequently used for the treatment of Helicobacter pylori infection. These regimens fail to eradicate H pylori in 15% to 40% of patients, primarily due to antimicrobial resistance and insufficient patient compliance. Effective prevention and eradication of H pylori by passive immunization with orally administered bovine antibodies has been demonstrated in animal studies, and may serve as an alternative therapy in humans.http://dx.doi.org/10.1155/2011/672093 |
| spellingShingle | CM den Hoed AC de Vries PBF Mensink CM Dierikx H Suzuki L Capelle H van Dekken R Ouwendijk EJ Kuipers Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial Canadian Journal of Gastroenterology |
| title | Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial |
| title_full | Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial |
| title_fullStr | Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial |
| title_full_unstemmed | Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial |
| title_short | Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial |
| title_sort | bovine antibody based oral immunotherapy for reduction of intragastric helicobacter pylori colonization a randomized clinical trial |
| url | http://dx.doi.org/10.1155/2011/672093 |
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