Cognitive Performance Among Older Adults with Subjective Cognitive Decline
<b>Objectives:</b> The main objective of this cross-sectional study was to investigate if there are significant differences in cognition between a group of older adults with subjective cognitive decline (SCD) and cognitively intact controls. <b>Methods:</b> An initial sample...
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MDPI AG
2025-03-01
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| Series: | Geriatrics |
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| Online Access: | https://www.mdpi.com/2308-3417/10/2/39 |
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| author | Ramón López-Higes Susana Rubio-Valdehita David López-Sanz Sara M. Fernandes Pedro F. S. Rodrigues María Luisa Delgado-Losada |
| author_facet | Ramón López-Higes Susana Rubio-Valdehita David López-Sanz Sara M. Fernandes Pedro F. S. Rodrigues María Luisa Delgado-Losada |
| author_sort | Ramón López-Higes |
| collection | DOAJ |
| description | <b>Objectives:</b> The main objective of this cross-sectional study was to investigate if there are significant differences in cognition between a group of older adults with subjective cognitive decline (SCD) and cognitively intact controls. <b>Methods:</b> An initial sample of 132 older people underwent an extensive neuropsychological evaluation (memory, executive functions, and language) and were classified according to diagnostic criteria. Two groups of 33 subjects each, controls and SCD, were formed using an a priori case-matching procedures in different variables: age, biological sex, years of education, cognitive reserve, and Mini-Mental State Exam. <b>Results:</b> The mean age and standard deviation in the control group were equal to 70.39 ± 4.31 years, while in the SCD group, they were 70.30 ± 4.33 years. The number of males (<i>n</i> = 9) and females (<i>n</i> = 24) was equal in both groups; the means of years of education were also quite similar. SCD participants have a significantly lower mood than the controls. Significant differences between groups were obtained in delayed recall, inhibitory control, and comprehension of sentences not fitted to canonical word order in Spanish. A logistic regression revealed that a lower score on the Stroop’s interference condition is associated with a higher likelihood of having SCD. Finally, ROC analysis provided a model that performs better than random chance, and a cut-off score in Stroop’s interference condition equal to 49 was suggested for clinically differentiating the two groups. <b>Conclusions:</b> This study highlights that, compared to a matched control group, participants with SCD showed subtle but significant neuropsychological differences. |
| format | Article |
| id | doaj-art-83ff136eb3c74d49b1ae75b3469cba7c |
| institution | OA Journals |
| issn | 2308-3417 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Geriatrics |
| spelling | doaj-art-83ff136eb3c74d49b1ae75b3469cba7c2025-08-20T02:28:23ZengMDPI AGGeriatrics2308-34172025-03-011023910.3390/geriatrics10020039Cognitive Performance Among Older Adults with Subjective Cognitive DeclineRamón López-Higes0Susana Rubio-Valdehita1David López-Sanz2Sara M. Fernandes3Pedro F. S. Rodrigues4María Luisa Delgado-Losada5Departamento de Psicología Experimental, Complutense University of Madrid (UCM), 28223 Madrid, SpainDepartamento de Psicología Social, del Trabajo y Diferencial, Complutense University of Madrid (UCM), 28223 Madrid, SpainDepartamento de Psicología Experimental, Complutense University of Madrid (UCM), 28223 Madrid, SpainCINTESIS.UPT@RISE-Health, Portucalense University, 4200-072 Porto, PortugalCINTESIS.UPT@RISE-Health, Portucalense University, 4200-072 Porto, PortugalDepartamento de Psicología Experimental, Complutense University of Madrid (UCM), 28223 Madrid, Spain<b>Objectives:</b> The main objective of this cross-sectional study was to investigate if there are significant differences in cognition between a group of older adults with subjective cognitive decline (SCD) and cognitively intact controls. <b>Methods:</b> An initial sample of 132 older people underwent an extensive neuropsychological evaluation (memory, executive functions, and language) and were classified according to diagnostic criteria. Two groups of 33 subjects each, controls and SCD, were formed using an a priori case-matching procedures in different variables: age, biological sex, years of education, cognitive reserve, and Mini-Mental State Exam. <b>Results:</b> The mean age and standard deviation in the control group were equal to 70.39 ± 4.31 years, while in the SCD group, they were 70.30 ± 4.33 years. The number of males (<i>n</i> = 9) and females (<i>n</i> = 24) was equal in both groups; the means of years of education were also quite similar. SCD participants have a significantly lower mood than the controls. Significant differences between groups were obtained in delayed recall, inhibitory control, and comprehension of sentences not fitted to canonical word order in Spanish. A logistic regression revealed that a lower score on the Stroop’s interference condition is associated with a higher likelihood of having SCD. Finally, ROC analysis provided a model that performs better than random chance, and a cut-off score in Stroop’s interference condition equal to 49 was suggested for clinically differentiating the two groups. <b>Conclusions:</b> This study highlights that, compared to a matched control group, participants with SCD showed subtle but significant neuropsychological differences.https://www.mdpi.com/2308-3417/10/2/39subjective cognitive declinehealthy older adultsmemoryexecutive functionslanguage |
| spellingShingle | Ramón López-Higes Susana Rubio-Valdehita David López-Sanz Sara M. Fernandes Pedro F. S. Rodrigues María Luisa Delgado-Losada Cognitive Performance Among Older Adults with Subjective Cognitive Decline Geriatrics subjective cognitive decline healthy older adults memory executive functions language |
| title | Cognitive Performance Among Older Adults with Subjective Cognitive Decline |
| title_full | Cognitive Performance Among Older Adults with Subjective Cognitive Decline |
| title_fullStr | Cognitive Performance Among Older Adults with Subjective Cognitive Decline |
| title_full_unstemmed | Cognitive Performance Among Older Adults with Subjective Cognitive Decline |
| title_short | Cognitive Performance Among Older Adults with Subjective Cognitive Decline |
| title_sort | cognitive performance among older adults with subjective cognitive decline |
| topic | subjective cognitive decline healthy older adults memory executive functions language |
| url | https://www.mdpi.com/2308-3417/10/2/39 |
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