Cocaine-Induced Giant Bullous Emphysema

Background. Emphysematous bullae, defined as airspaces of greater than or equal to one centimeter in diameter, have a variety of etiologies such as tobacco use and alpha-1 antitrypsin being the most common. Emphysematous bullae have also been reported in patients using cocaine usually involving the...

Full description

Saved in:
Bibliographic Details
Main Authors: Steven Douedi, Vandan D. Upadhyaya, Ishan Patel, Usman Mazahir, Eric Costanzo, Mohammad A. Hossain
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/6410327
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566550517776384
author Steven Douedi
Vandan D. Upadhyaya
Ishan Patel
Usman Mazahir
Eric Costanzo
Mohammad A. Hossain
author_facet Steven Douedi
Vandan D. Upadhyaya
Ishan Patel
Usman Mazahir
Eric Costanzo
Mohammad A. Hossain
author_sort Steven Douedi
collection DOAJ
description Background. Emphysematous bullae, defined as airspaces of greater than or equal to one centimeter in diameter, have a variety of etiologies such as tobacco use and alpha-1 antitrypsin being the most common. Emphysematous bullae have also been reported in patients using cocaine usually involving the lung periphery and sparing the central lung parenchyma. We present a case of a male with a history of cocaine abuse found to have a singular giant emphysematous bulla occupying >95% of the right hemithorax requiring video-assisted thoracic surgery (VATS) with a favorable outcome. Case Presentation. A 50-year-old male with a history of chronic cocaine abuse was found unresponsive in the field and given multiple doses of naloxone without any improvement in mental status. On presentation to the emergency department, chest X-ray as well as CT scan of the chest were performed which were suggestive of an extensive pneumothorax of the right lung requiring placement of a chest tube. The patient was subsequently intubated and underwent bronchoscopy with right chest VATS which found a giant bulla encasing the entire right pleural cavity. During the procedure, he underwent resection of the bullae and a partial right pleurodesis. After the procedure, patient’s respiratory status significantly improved, and he was discharged in a stable condition. Conclusion. Cocaine use is a rare but identifiable factor that can cause giant bullous emphysema (GBE) resulting in severe complications and even death. The purpose of this case presentation is to support early identification and treatment of GBE using bullectomy with VATS, improving outcomes and decreasing morbidity and mortality.
format Article
id doaj-art-83e975759c5e4b378c373c84f2ecb982
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-83e975759c5e4b378c373c84f2ecb9822025-02-03T01:03:48ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/64103276410327Cocaine-Induced Giant Bullous EmphysemaSteven Douedi0Vandan D. Upadhyaya1Ishan Patel2Usman Mazahir3Eric Costanzo4Mohammad A. Hossain5Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USADepartment of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USADepartment of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USADepartment of Pulmonary and Critical Care Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USADepartment of Pulmonary and Critical Care Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USADepartment of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USABackground. Emphysematous bullae, defined as airspaces of greater than or equal to one centimeter in diameter, have a variety of etiologies such as tobacco use and alpha-1 antitrypsin being the most common. Emphysematous bullae have also been reported in patients using cocaine usually involving the lung periphery and sparing the central lung parenchyma. We present a case of a male with a history of cocaine abuse found to have a singular giant emphysematous bulla occupying >95% of the right hemithorax requiring video-assisted thoracic surgery (VATS) with a favorable outcome. Case Presentation. A 50-year-old male with a history of chronic cocaine abuse was found unresponsive in the field and given multiple doses of naloxone without any improvement in mental status. On presentation to the emergency department, chest X-ray as well as CT scan of the chest were performed which were suggestive of an extensive pneumothorax of the right lung requiring placement of a chest tube. The patient was subsequently intubated and underwent bronchoscopy with right chest VATS which found a giant bulla encasing the entire right pleural cavity. During the procedure, he underwent resection of the bullae and a partial right pleurodesis. After the procedure, patient’s respiratory status significantly improved, and he was discharged in a stable condition. Conclusion. Cocaine use is a rare but identifiable factor that can cause giant bullous emphysema (GBE) resulting in severe complications and even death. The purpose of this case presentation is to support early identification and treatment of GBE using bullectomy with VATS, improving outcomes and decreasing morbidity and mortality.http://dx.doi.org/10.1155/2020/6410327
spellingShingle Steven Douedi
Vandan D. Upadhyaya
Ishan Patel
Usman Mazahir
Eric Costanzo
Mohammad A. Hossain
Cocaine-Induced Giant Bullous Emphysema
Case Reports in Medicine
title Cocaine-Induced Giant Bullous Emphysema
title_full Cocaine-Induced Giant Bullous Emphysema
title_fullStr Cocaine-Induced Giant Bullous Emphysema
title_full_unstemmed Cocaine-Induced Giant Bullous Emphysema
title_short Cocaine-Induced Giant Bullous Emphysema
title_sort cocaine induced giant bullous emphysema
url http://dx.doi.org/10.1155/2020/6410327
work_keys_str_mv AT stevendouedi cocaineinducedgiantbullousemphysema
AT vandandupadhyaya cocaineinducedgiantbullousemphysema
AT ishanpatel cocaineinducedgiantbullousemphysema
AT usmanmazahir cocaineinducedgiantbullousemphysema
AT ericcostanzo cocaineinducedgiantbullousemphysema
AT mohammadahossain cocaineinducedgiantbullousemphysema